Results 31 to 40 of about 119,963 (264)
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Empowering Adult Learning How AI Fuels Progress Across Disciplines and Professions
ABSTRACT This article examines the evolving role of artificial intelligence (AI) as a transformative cognitive partner across educational and professional fields. It explores how AI shifts attention away from routine technical tasks and toward human‐centered skills such as critical thinking, ethical decision‐making, and professional judgment.
Rachel Wlodarsky
wiley +1 more source
ABSTRACT This article examines the evolving role of organizational leadership amidst the rapid advancements in artificial intelligence (AI). It explores a broadly experienced and documented crisis in leadership, due in part to the disruptive nature of AI and emerging technology.
Rachel Wlodarsky, Davin Carr Chellman
wiley +1 more source
Adolescent Pregnancy: A Phenomenological Approach [PDF]
Pregnancy before the age of 20 carries a higher risk of complications during both pregnancy and childbirth. Adolescent pregnancy is a global issue that contributes significantly, up to five times more, to maternal and neonatal mortality rates. In Central
Kiriwenno Erlin +3 more
doaj +1 more source
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh +5 more
wiley +1 more source
Brugbouer tussen generasies: Koos Roets se samewerkingsnetwerk in die Afrikaanse filmbedryf
Bridge builder between generations: Koos Roets’s cooperation network in the Afrikaans film industry. Koos Roets’s contribution to the Afrikaans film industry is widely recognised.
Burgert A. Senekal, Cornelia Geldenhuys
doaj +1 more source
This article presents the NFDI‐MatWerk Ontology (MWO), a Basic Formal Ontology‐based framework for interoperable research data management in materials science and engineering (MSE). Covering consortium structures, research data management resources, services, and instruments, MWO enables semantic integration, Findable, Accessible, Interoperable, and ...
Hossein Beygi Nasrabadi +4 more
wiley +1 more source
Empowerment in IT Education [PDF]
Introduction This paper addresses a subject which, at first sight, may not seem directly relevant to IT education. The first part of the paper, therefore, explains what we mean by empowerment and why we think it is highly relevant, worthwhile and fun! The remainder of the paper shows how students can be empowered with examples drawn from our combined ...
Ray J. Dawson, Ian A. Newman
openaire +1 more source

