Results 111 to 120 of about 107,853 (287)
Advanced Science, EarlyView.A single‐cell atlas of pancreatic ductal adenocarcinoma development reveals progressive ductal‐fibroblast‐immune crosstalk. Tumor‐derived LAMB3 drives the formation of immunosuppressive LRRC15+ fibroblasts through the ITGB1/FAK/MAPK/FOSL2 signaling. Glycolytic reprogramming upregulates LAMB3 and correlates with LRRC15+ fibroblast enrichment.
Xuqing Shi +23 more
wiley +1 more source
Body composition and weight changes of mature grazing Angus cows
, 1979 In vivo body composition was estimated by both direct and indirect methods 33 times on 18 mature Angus cows grazing either high or low quality pasture. The direct method consisted of deuterium oxide in a deuterium oxide dilution technique employing a two
Brown, William Francis
core
Effect of TLR4 siRNA and PDTC treatment on food intake and body weight in CUMS apoE-/- mice.
, 2015 (A) Food intake and (B) Body weight were determined at week 12 of experimental procedure. Food intake and body weight in CUMS mice significantly decreased compared with that in control ones, respectively.
Shuang Wang (46453) +7 more
core +1 more source
Advanced Science, EarlyView.The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi +8 more
wiley +1 more source
Advanced Science, EarlyView.HNRNPD promotes radioresistance in nasopharyngeal carcinoma by enhancing stress granule assembly and sequestering GRAMD4 mRNA. This suppresses GRAMD4 translation and inhibits mitochondrial apoptosis. Targeting the integrated stress response with ISRIB restores GRAMD4 expression and sensitizes tumors to radiotherapy, revealing a translational control ...
Yingzi Li +13 more
wiley +1 more source
Advanced Science, EarlyView.This study identifies ARID3A as a key immunosuppressive transcription factor in TNBC. Its inhibition activates the type I IFN pathway, boosting CD8+ T cell infiltration and sensitizing tumors to anti‐PD‐1. The FDA‐approved migraine drug Rimegepant targets ARID3A, enhances immunotherapy efficacy in preclinical models, and establishes a druggable axis to
Teng Zhou +12 more
wiley +1 more source
Effects of dietary changes on heat stress in broiler and Kampung chickens
, 2012 Poultry meat production has increased drastically over the last 35 years. Most developing countries are in the tropics and often have high ambient temperatures.
Syafwan, W.
core
Relationship between fetal skull size and body weight in low protein and control groups.
, 2016 A) Linear regressions between log centroid size (CS) and log body weight (BW) for the cranium, face and neurocranium; B) residuals of linear regressions between log CS and BW.
Malgorzata Gasperowicz (2577196) +5 more
core +1 more source
Advanced Science, EarlyView.Cigarette smoke accelerates the aging of immune cells in the lung. By combining human single‐cell sequencing, cell culture, and mouse models, the authors show that the protein GEM drives mitochondrial damage and senescence in alveolar macrophages by suppressing SIRT3.
Jin Wang +8 more
wiley +1 more source
Trace mineral requirements for growth of Moxotó goats grazing in the semiarid region of Brazil
Revista Brasileira de ZootecniaA comparative slaughter trial was conducted to estimate the body composition and net requirements of Cu, Zn, Mn, Fe, and Co for growth of castrated Moxotó goat kids, with15.69±0.78 kg initial body weight (BW), grazing in the semiarid region of Brazil ...
Marcos Jácome de Araújo +6 more
doaj +1 more source