Results 61 to 70 of about 40,617 (277)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Vulcan might have existed, and Neptune not : On the Semantics of Empty Names

, 2014
Empty names such as ‘Vulcan’ or ‘Sherlock Holmes’ have intrigued philosophers of language at least since Frege. They are clearly problematic for Millian accounts of the semantics of proper names, but also for certain recent versions of descriptivism ...
Glüer, Kathrin,, Pagin, Peter,
core  

THE PRECEDENT NAME IN THE MASS MEDIA TEXT: IMAGE OF SHVONDER AS A MEAN OF CHARACTERIZATION AND ESTIMATION

RUDN Journal of Language Studies, Semiotics and Semantics, 2019
The precedent phenomena, to which the names of the heroes of literary works belong, are very typical for modern journalistic texts “charged primarily with negative emotions” (V.I.
Elena I. Seliverstova
doaj   +1 more source

Patterns of pesticide usage in agriculture in rural Tanzania call for integrating agricultural and public health practices in managing insecticide-resistance in malaria vectors

Malaria Journal, 2020
Background Unrestricted use of pesticides in agriculture is likely to increase insecticide resistance in mosquito vectors. Unfortunately, strategies for managing insecticide resistance in agriculture and public health sectors lack integration. This study
Nancy S. Matowo, Marcel Tanner, Givemore Munhenga, Salum A. Mapua, Marceline Finda, Jürg Utzinger, Vera Ngowi, Fredros O. Okumu   +7 more
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Empty Names and Reference

, 2003
The problem of empty names derives from the fact that empty names fail to refer. The reference failure of empty names implies that sentences containing empty names lack truth-conditions. As a consequence those sentences are meaningless, according to many
Bjurman, Anna
core  

Two Theories of Names

, 2002
The aim of this paper is to assess the relative merits of two accounts of the semantics of proper names. The enterprise is of particular interest because the theories are very similar in fundamental respects.
Gabriel M. A. Segal
core   +1 more source

Risk of Non‐Arteritic Anterior Ischemic Optic Neuropathy in Idiopathic Intracranial Hypertension Patients Treated with GLP‐1 Receptor Agonists

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) have demonstrated significant weight‐reducing effects and may offer benefits in idiopathic intracranial hypertension (IIH); however, recent concerns about the risk of non‐arteritic anterior ischemic optic neuropathy (NAION) have emerged.
Faisal A. Al‐Harbi, Mohanad A. Alkuwaiti, Yazeed B. Alaql, Ahmed K. Alsaif, Ahmed A. Alessa, Meshari Ayed Alharbi, Mohammed Alfalah, Saud A. Alnaaim, Sajjad M. AlHaddad, Ahmed Y. Azzam   +9 more
wiley   +1 more source

Quantificational Logic and Empty Names [PDF]

, 2013
The result of combining classical quantificational logic with modal logic proves necessitism – the claim that necessarily everything is necessarily identical to something.
Bacon, Andrew
core   +1 more source

A formalization of Descartes’ causal argument for existence of God

Principia: An International Journal of Epistemology
In this paper I attempt a formalization of Descartes’ causal argument for the existence of God presented in the Third Meditation. By taking into account the philosophical setting of Descartes’ Meditations, I argue that the best logical theory to carry ...
Vincenzo Ciccarelli
doaj   +1 more source