Results 61 to 70 of about 1,396,264 (177)

CHARGE Syndrome: A Narrative Review and Update on Diagnosis, Assessment and Management

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Background CHARGE syndrome (CS) is a rare multisystemic genetic condition caused by a pathogenic variant in the DNA‐binding protein‐7 CHD7 gene. The condition affects the development of neural crest cells, which give rise to craniofacial structures, cranial nerves, ears, eyes and the heart, resulting in diverse and complex clinical features ...
Eleni M. van Gelder, Suzanna E. L. Temple, Niall Jefferson, David Brown, Kasee Stratton‐Gadke, Madelene Rich, Steve Rose, Kim Blake   +7 more
wiley   +1 more source

Olfactory structure and olfactory content

Mind &Language, EarlyView.
The philosophical literature on olfaction is characterized by diverging opinions on the spatiality of olfactory experiences. Some authors believe that olfactory experiences merely present entities as being “here”, but others postulate that such experiences present a rich array of spatial relations.
Błażej Skrzypulec
wiley   +1 more source

Atypical Facial Pain in a 16-year-old Girl: A Case Report

مجله دانشکده پزشکی اصفهان, 2009
Case Report We report a case of atypical facial pain in a 16-year-old girl who was admitted to the kashani clinic because of pain in the left side of face, weight loss, and depression.
Mostafi Hashemi, Zahra Danesh, Maryam Karim   +2 more
doaj  

Voltage‐gated potassium channels mediate thyroid hormone control of skeletal muscle excitability

The Journal of Physiology, EarlyView.
Abstract figure legend Thyroid hormone (TH)‐dependent remodelling of potassium (K+) channel networks regulates skeletal muscle (SkM) excitability. Triiodothyronine (T3), locally generated from thyroxine (T4) by type 2 deiodinase (D2), binds thyroid hormone receptors (TRα/β) and modulates transcription via thyroid response elements (TREs).
Annarita Nappi, Caterina Miro, Annunziata Gaetana Cicatiello, Ilaria Piccialli, Serena Sagliocchi, Lucia Acampora, Federica Restolfer, Rosa Sirica, Melania Murolo, Emery Di Cicco, Daniela Terracciano, Anna Pannaccione, Monica Dentice   +12 more
wiley   +1 more source

The E3 Ubiquitin Ligase RLIM Safeguards Oligodendrocyte Development and Myelination by Targeting SLC7A11 for Polyubiquitination to Regulate Ferroptotic Resistance

Advanced Science, Volume 13, Issue 53, 24 September 2026.
RLIM‐mediated SLC7A11 polyubiquitination is required for SPTBN2‐mediated trafficking and membrane localization of SLC7A11, which enables oligodendrocyte precursor cells to be resistant to ferroptosis and safeguards oligodendrocyte lineage progression and thus myelination.
Yuwei Li, Haijun Zhang, Jieya Zhou, Shiyu Yang, Jingmei Cha, Gaofeng Yan, Shuhua Zhao, Bingyu Mao, Pengcheng Ma   +8 more
wiley   +1 more source

Concomitant Lemierre's Syndrome and Base‐of‐Skull Osteomyelitis Caused by Arcanobacterium haemolyticum, Complicated by Ceftriaxone‐Associated Cholecystitis: A Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Lemierre's syndrome and base‐of‐skull osteomyelitis can occur together in immunocompetent adolescents with Arcanobacterium haemolyticum bacteraemia. Prolonged high‐dose ceftriaxone may precipitate symptomatic cholecystitis. Clinicians should consider A.
Angus Lane, Alexandra Stewart
wiley   +1 more source

This familiar diagnosis of “rhinitis”

Медицинский совет, 2020
The article highlights that rhinitis is the most common disease, it is divided into 3 main phenotypes: infectious (IR), allergic (AR) and non-infectious non-allergic (NAR). There are also combined forms.IR is a viral disease.
G. D. Tarasova, I. M. Kirichenko, E. V. Mirzabekyan   +2 more
doaj   +1 more source

Ganoderic Acid A Ameliorates Pentylenetetrazol‐Induced Epilepsy in Mice via Activating KCNQ2

CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
GA‐A binds and activates KCNQ2, thereby reducing epileptic‐like EEG discharges, the loss and apoptosis of hippocampal neurons, and improving anxiety and depression‐like behavioral changes. In addition, GA‐A inhibits neuroinflammation and alleviates oxidative stress independent of activating KCNQ2.
Yang Yao, Zhujun Liu, Xujiao Wang, Cunhao Bian, Rui Wang, Yukun Zhang   +5 more
wiley   +1 more source

Lysosomal Dysfunction Is Associated With Intervertebral Disc Degeneration: Multiomics and Machine Learning Identify Molecular Subtypes and Hub Genes

The Journal of Gene Medicine, Volume 28, Issue 9, September 2026.
Intervertebral disc degeneration (IVDD) is linked to lysosomal dysfunction, impaired autophagic degradation, and cellular senescence. Integrating bulk and single‐cell transcriptomics with machine learning, this study identified two lysosome‐related molecular subtypes and four hub genes: HYAL1, MMD, PLD3, and ANK3.
Yang Yang, Hong Li, Yixuan Ou, Yaping Yu, Kaiqiang Sun, Shixing Chen, Chenglong Ji   +6 more
wiley   +1 more source

Evaluation of sinonasal-related quality of life of 49 patients undergoing endoscopic skull base surgery

Brazilian Journal of Otorhinolaryngology
Objective: This study aimed to evaluate the sinonasal-related Quality of Life (QoL) in patients undergoing endoscopic skull base surgery. Methods: A retrospective study was performed, including patients with benign and malignant tumors at a single ...
Yijie Zhong, Zeyi Deng, Hailing Chen, Qianhui Qiu   +3 more
doaj   +1 more source