Results 231 to 240 of about 187,158 (266)

Peptide RL‐QN15 Regulates Functions of Epidermal Stem Cells to Accelerate Skin Wound Regeneration via the FZD8/β‐Catenin Axis

Exploration, EarlyView.
Amphibian‐derived peptide RL‐QN15 activates the Wnt/β‐catenin signaling pathway by interacting with the FZD8 membrane receptor, promoting epidermal stem cells proliferation, migration, stemness, and EMT processes, thus promoting skin wound healing.
Yuansheng Li, Qiuye Jia, Naixin Liu, Saige Yin, Junyuan Wang, Yujing Ding, Yuliu Yang, Ying Peng, Zeqiong Ru, Shaoyang Zhang, Bu'er Qi, Jun Sun, Li He, Ying Wang, Kun Guo, Xinwang Yang   +15 more
wiley   +1 more source

Non-linear saturation threshold of gonadotropin dose on cumulative live birth rates in advanced-age women with polycystic ovary syndrome: a retrospective cohort study. [PDF]

Front Endocrinol (Lausanne)
Han Y, Wei C, Wang X, Zhang J.
europepmc   +1 more source

CCL26‐Mediated Modulation of Endothelial Secretome by Hypoxia‐Induced Tumor‐Derived Exosomes Enhances Metastatic Progression in Head and Neck Cancer

Head &Neck, EarlyView.
ABSTRACT Background Tumor cells adapt to hypoxia by releasing hiTDExs enriched with bioactive molecules that modulate endothelial behavior and promote tumor progression. This study aimed to characterize how hypoxia‐induced HNSCC exosomes reshape the endothelial secretome and contribute to metastatic potential.
Ozel Capik, Sevil Tekman, Betul Gundogdu, Ahsen Kilic, Rumeysa Polat, Omer Aydin, Omer Faruk Karatas   +6 more
wiley   +1 more source

Autophagy-epithelial-mesenchymal transition crosstalk in acute respiratory distress syndrome: Mechanistic insights and therapeutic perspectives (Review). [PDF]

Exp Ther Med
Zhang Y, He H, Dong C, Guo Q, Tan J, Yang Y, Guo Z, Zhang R.   +7 more
europepmc   +1 more source

Multi-omics single-cell dissection of malignant epithelial heterogeneity identifies GJB2 as an EMT-driving biomarker in triple-negative breast cancer. [PDF]

BMC Med Genomics
Xu H, Zhang C, Zhang X, Zhang S, Zhou G.
europepmc   +1 more source

MUC1 as a Survival Effector of Radiotherapy‐Induced Epithelial Hybrid States in Basal‐Like Breast Cancer

International Journal of Cancer, EarlyView.
Basal‐like breast cancer (BLBC) is aggressive and often exhibits inherent or acquired resistance to radiotherapy (RT), a primary treatment option. RT resistance is underpinned by molecular alterations, many of which are poorly understood. Here, RT‐induced transcriptomic changes were analyzed using bulk and spatial sequencing in a BLBC mouse model and ...
Garyfallia Pantelaiou‐Prokaki, Husam Bamahmoud, Nadine S. Georges, Shaishavi Jansari, Annika Jung, Daniela Grimm, Evangelos Prokakis, Fabian Alexander Gayer, Maryam Deldar, Christian Dullin, Julia Gallwas, Florian Wegwitz, Frauke Alves   +12 more
wiley   +1 more source

Integrated Genomic and Single-Cell Analysis Identifies Notch1 as a Metastasis Suppressor in Nasopharyngeal Carcinoma Targeted by the AKT/Smad3 Axis. [PDF]

Biol Proced Online
Zuo J, Huang S, Dai M, Li F, Huang T, Wang L, Qi C, Tao Z, Ye L.   +8 more
europepmc   +1 more source

<i>H19</i>/miR-675 Axis Promotes Cancer Metastasis by Orchestrating EMT and MET Processes. [PDF]

Cells
Klouyovo K, Le Bourhis X, Adriaenssens É.   +2 more
europepmc   +1 more source

Clinicopathological and Prognostic Implications of Epithelial-to-Mesenchymal Transition-Related Immunohistochemical Markers in Resectable Pancreatic Cancer: A Retrospective Longitudinal Study. [PDF]

Cancer Rep (Hoboken)
Machmouchi A, Zahreddine L, Aoun J, Abbas N, Charafeddine M, Chehade L, Elias C, El Husseini Z, Temraz S, Mukherji D, Khalife M, Faraj W, Zaidan A, Kadi N, Tawil A, Shamseddine A.   +15 more
europepmc   +1 more source

Single cell multiomics unravel the transcription networks controlling the different EMT tumor states

González AP, Windels G, Bévant K, Lengrand J, Lemaire S, Moers V, Scozzaro S, Debroux U, Dubois C, Vanuytven S, Blanpain C.   +10 more
europepmc   +1 more source