Results 251 to 260 of about 338,860 (400)

Role of epithelial-to-mesenchymal transition (EMT) in drug sensitivity and metastasis in bladder cancer [PDF]

open access: green, 2009
David J. McConkey   +11 more
openalex   +1 more source

Distinct CTC Specific RNA Profile Enables NSCLC Early Detection and Dynamic Monitoring of Advanced NSCLC

open access: yesAdvanced Science, EarlyView.
A quantitative CTC RNA assay is developed by incorporating multi‐antibody‐based CTC isolation and specific mRNA quantification using RT‐ddPCR. The NSCLC CTC ScoreD demonstrates high accuracy for early‐stage NSCLC detection, significantly outperforming serum CEA. NSCLC CTC ScoreM exhibits a more accurate early‐warning of responses to different therapies
Xiaoyu Wang   +14 more
wiley   +1 more source

Cancer Metastasis Is Accelerated through Immunosuppression during Snail-Induced EMT of Cancer Cells [PDF]

open access: bronze, 2009
Chie Kudo‐Saito   +3 more
openalex   +1 more source

A Self‐Assembling LYTAC Mediates CTGF Degradation and Remodels Inflammatory Tumor Microenvironment for Triple‐Negative Breast Cancer Therapy

open access: yesAdvanced Science, EarlyView.
A CTGF‐LYTAC nanoplatform is developed to selectively degrade connective tissue growth factor (CTGF) in triple‐negative breast cancer (TNBC), inhibiting TGF‐β signaling and cell interactions in the tumor microenvironment (TME). This strategy effectively suppresses tumor growth and metastasis, outperforming antibody‐based therapy.
Jia‐Yi Lin   +11 more
wiley   +1 more source

TGF-β induces EMT in thyroid cancer cells by regulating transcription factors. [PDF]

open access: yesThyroid Res
Xiang J   +7 more
europepmc   +1 more source

A Gene Expression Signature Associated with “K-Ras Addiction” Reveals Regulators of EMT and Tumor Cell Survival [PDF]

open access: bronze, 2009
Anurag Singh   +6 more
openalex   +1 more source

Paracrine Orchestration of Tumor Microenvironment Remodeling Induced by GLO1 Potentiates Lymph Node Metastasis in Breast Cancer

open access: yesAdvanced Science, EarlyView.
Single‐cell RNA sequencing of lymph node (LN) samples is performed, and a comprehensive landscape of the entire ecosystem is generated. Paracrine orchestration of TME remodeling induced by GLO1 potentiates LN metastasis in breast cancer. This study offers novel perspectives on the microenvironment remodeling of breast cancer LN metastases, suggesting ...
Jindong Xie   +16 more
wiley   +1 more source

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