Results 1 to 10 of about 23,157 (220)
Pharmaceutics, 2014 Vaginal tablets are being developed as an alternative to gels as an inexpensive, discreet dosage form for the administration of microbicides. This work describes the pharmacokinetic (PK) evaluation of rapidly disintegrating vaginal tablets containing ...
Meredith Clark +2 more
exaly +3 more sources
Molecules, 2020 This study was aimed to find out the solubility, thermodynamic behavior, Hansen solubility parameters and molecular interactions of an antiviral drug emtricitabine (ECT) in various “[polyethylene glycol-400 (PEG-400) + water]” mixtures. The solubility of
Ibrahim Alsarra, , Faiyaz Shakeel
exaly +3 more sources
Pharmaceutics, 2022 Nucleos(t)ide reverse transcriptase inhibitors (NRTIs) are the backbone of HIV antiretroviral therapy (ART). ART use in pregnancy has been associated with adverse birth outcomes, in part due to NRTI-induced mitochondrial toxicity.
Kayode Balogun, Lena Serghides
doaj +1 more source
Combination Antiretroviral Therapy and Immunophenotype of Feline Immunodeficiency Virus
Viruses, 2023 Feline Immunodeficiency Virus (FIV) causes progressive immune dysfunction in cats similar to human immunodeficiency virus (HIV) in humans. Although combination antiretroviral therapy (cART) is effective against HIV, there is no definitive therapy to ...
Jeffrey Kim +8 more
doaj +1 more source
HIV Research & Clinical Practice, 2021 Background: Evidence from clinical practice on the effects of switching from emtricitabine/tenofovir disoproxil fumarate (F/TDF) to emtricitabine/tenofovir alafenamide (F/TAF)-based triple-therapy (TT) regimens on renal parameters is limited.
Ramón Teira +21 more
doaj +1 more source
A case series of emtricitabine-induced pure red cell aplasia
Southern African Journal of HIV Medicine, 2021 Background: Anaemia is common in patients with retroviral disease. New or worsening anaemia after initiation of antiretroviral (ARV) treatment has a broad differential diagnosis.
Nithendra Manickchund +5 more
doaj +1 more source
Pharmaceutics, 2023 Dose recommendations for lamivudine or emtricitabine in children with HIV and chronic kidney disease (CKD) are absent or not supported by clinical data.
Tom G. Jacobs +7 more
doaj +1 more source
Frontiers in Reproductive Health, 2023 ObjectiveTo evaluate upward-adjustment of tenofovir disoproxil fumarate (TDF)/emtricitabine (FTC) pre-exposure prophylaxis (PrEP) dosing during pregnancy in order to maintain target plasma concentrations associated with HIV protection.DesignPopulation ...
Rachel K. Scott +5 more
doaj +1 more source
Preclinical Evaluation of Long-Acting Emtricitabine Semi-Solid Prodrug Nanoparticle Formulations
Pharmaceutics, 2023 Long-acting injectable (LAI) formulations promise to deliver patient benefits by overcoming issues associated with non-adherence. A preclinical assessment of semi-solid prodrug nanoparticle (SSPN) LAI formulations of emtricitabine (FTC) is reported here.
Paul Curley +16 more
doaj +1 more source
Frontiers in Immunology, 2021 Microglia, the resident brain phagocytes, likely play a key role in human immunodeficiency virus (HIV) infection of the central nervous system (CNS) and subsequent neuropathogenesis; however, the nature of the infection-induced changes that yield ...
Joseph W. George +6 more
doaj +1 more source