Results 111 to 120 of about 217,999 (303)

Editorial: Microencapsulation for Biomedical Applications

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Aurelio Salerno   +5 more
doaj   +1 more source

Sustained Delivery of a Shingles Subunit Vaccine Overcomes Age‐Related Declines in Humoral and Cellular Immunity Relative to Shingrix

open access: yesAdvanced Science, EarlyView.
Sustained delivery of a shingles subunit vaccine from an injectable polymer–nanoparticle hydrogel enhanced the potency, durability, and breadth of immune responses in aged mice while minimizing inflammatory cytokine production and reactogenicity. This strategy decouples immunogenicity from reactogenicity and offers a promising approach to improve ...
Ye Eun Song   +5 more
wiley   +1 more source

Microenvironment‐Responsive Nanomedicine Enables Vertical Modulation of Mitochondrial Pathological Networks in Myocardial Ischemia–Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
A mitochondria‐targeted, microenvironment‐responsive nanoplatform enables pH/ROS‐triggered co‐delivery of berberine and isoliensinine to orchestrate ROS scavenging, inflammation suppression, and apoptosis inhibition. This vertical modulation of mitochondrial pathological networks preserves mitochondrial function and effectively mitigates myocardial ...
Jue Wang   +11 more
wiley   +1 more source

Deconstruction of Human Age‐Related Cataract Capsules Defines Aging

open access: yesAdvanced Science, EarlyView.
We generate a comprehensive atlas of age‐related cataracts (ARC) at a single‐cell resolution, encompassing three disease states—mild cataract group (Mild), severe cortical cataract group (Severe_C), and severe nuclear cataract group (Severe_N). We find that ARC involves seven distinct lens capsule cell types, with notable differences in cellular ...
Qiaomei Tang   +9 more
wiley   +1 more source

Charge Regulation in Liquid Films Stabilized by Ionic Surfactants: Change in Adsorption with Film Thickness and Phase Transitions

open access: yesMolecules
When a liquid film is thinning, the charge and the potential of its surfaces change simultaneously due to the interaction between the two surfaces. This phenomenon is an example for charge regulation and has been known for half a century for systems ...
Iglika M. Dimitrova, Radomir I. Slavchov
doaj   +1 more source

Human‐Guided Bayesian Optimization Enables High‐Throughput Laser Annealing of Mesoporous SiOx Anodes for Lithium‐Ion Batteries

open access: yesAdvanced Science, EarlyView.
An empirical‐aided active learning framework is developed to optimize high‐throughput laser‐induced photothermal annealing of silicon suboxide anodes. By integrating probabilistic machine learning with empirical domain knowledge, this approach achieves optimal electrochemical performance using limited experiments.
Chaeyoung Park   +3 more
wiley   +1 more source

Influence of a Combination of Glycerol Polyethylene Glycol Ricinoleate and Bi-Distilled Oleic Acid in Powder Form on Growth Performance, Nutrient Digestibility, Excreta Nitrogen and Liver Fatty Acid Profile of Broilers Fed Reduced-Energy Diets

open access: yesAnimals
The present study aimed to evaluate the effects of an emulsifier in powder form composed of glycerol polyethylene glycol ricinoleate and bi-distilled oleic acid on the growth performance, nutrient digestibility, excreta nitrogen and liver fatty acid ...
Luca Marchetti   +7 more
doaj   +1 more source

Molecular Dynamics‐Guided Sterol Engineering of mRNA‐Lipid Nanoparticles Reprograms Biodistribution and Enhances Spleen‐Selective Immunity

open access: yesAdvanced Science, EarlyView.
Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon   +27 more
wiley   +1 more source

Dynamics and Stability Mechanism of Lactoferrin–EPA During Emulsification Process: Insights from Macroscopic and Molecular Perspectives

open access: yesFoods
Although eicosapentaenoic acid (EPA) as a functional fatty acid has shown significant benefits for human health, its susceptibility to oxidation significantly limits its application. In this study, we developed a nanoemulsion of the lactoferrin (LTF)–EPA
Han Tao   +5 more
doaj   +1 more source

Requirement for real-time water emulsion fuel supply system (RTES) concept design

open access: yes, 2015
Nowadays, demand for more efficient energ y increased due to the green technology as one of the promin ent research areas. In order to improve the exhaust emission from the diesel engine, researchers have found an alter na tive fuel which known as water ...
Mohamad, Zahari   +3 more
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