Results 61 to 70 of about 203,876 (244)

Ressenya a Emilio Callado (ed.), La catedral ilustrada. Iglesia, sociedad y cultura en la Valnecia del siglo XVIII, 2. vols. València, Institució Alfons el Magnànim, 2013-2014, 356 i 444 pp. ISBN: 978-84-7822-647-4 i 978-84-7822-667-2

open access: yesScripta: Revista Internacional de Literatura i Cultura Medieval i Moderna, 2015
Review to Emilio Callado (ed.), La catedral ilustrada. Iglesia, sociedad y cultura en la Valnecia del siglo XVIII, 2. vols. València, Institució Alfons el Magnànim, 2013-2014, 356 & 444 pp.
Marc Gandia Silvestre
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Estudio descriptivo de algunas variables emocionales en las personas mayores

open access: yesEuropean Journal of Investigation in Health, Psychology and Education, 2016
Se analizó el funcionamiento emocional (afecto positivo y negativo, satisfacción con la vida, soledad y estrategias de regulación) de las personas centenarias en comparación con el de personas de menor edad (65-74, 75-84 y 85-94 años). Participaron en el
Igone Etxeberria
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Calidad nutricional de la planta de ramio (bohemeria nivea (L) gaud) para alimentación animal

open access: yesAgronomía Mesoamericana, 2002
El presente experimento se llevó a cabo en la Estación Experimental de Ganado Lechero Alfredo Volio Mata, ubicada a 1542 msnm con una precipitación anual media de 2050 mm, temperatura media de 19,5 ºC y una humedad relativa de 84%.
Jorge Elizondo, Carlos Boschini
doaj  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

El alumno Gerber (Viena, 1929): algo más que un novela escolar

open access: yesHistoria y Memoria de la Educación, 2016
Reseña de los libros: El alumno Gerber, por Friedrich Torberg. Traducción del alemán de Marina Bornas Montaña. Barcelona, Acantilado, 2016, 317 pp. ISBN: 978-84-16011-91-9 La tía Jolesch, o la decadencia de Occidente en anécdotas, por Friedrich Torberg.
Raquel Cercós Raichs   +1 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

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