Results 61 to 70 of about 203,876 (244)
Review to Emilio Callado (ed.), La catedral ilustrada. Iglesia, sociedad y cultura en la Valnecia del siglo XVIII, 2. vols. València, Institució Alfons el Magnànim, 2013-2014, 356 & 444 pp.
Marc Gandia Silvestre
doaj +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Estudio descriptivo de algunas variables emocionales en las personas mayores
Se analizó el funcionamiento emocional (afecto positivo y negativo, satisfacción con la vida, soledad y estrategias de regulación) de las personas centenarias en comparación con el de personas de menor edad (65-74, 75-84 y 85-94 años). Participaron en el
Igone Etxeberria
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Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Calidad nutricional de la planta de ramio (bohemeria nivea (L) gaud) para alimentación animal
El presente experimento se llevó a cabo en la Estación Experimental de Ganado Lechero Alfredo Volio Mata, ubicada a 1542 msnm con una precipitación anual media de 2050 mm, temperatura media de 19,5 ºC y una humedad relativa de 84%.
Jorge Elizondo, Carlos Boschini
doaj
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
El alumno Gerber (Viena, 1929): algo más que un novela escolar
Reseña de los libros: El alumno Gerber, por Friedrich Torberg. Traducción del alemán de Marina Bornas Montaña. Barcelona, Acantilado, 2016, 317 pp. ISBN: 978-84-16011-91-9 La tía Jolesch, o la decadencia de Occidente en anécdotas, por Friedrich Torberg.
Raquel Cercós Raichs +1 more
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source

