Results 181 to 190 of about 3,133,392 (302)

Enablers of successful dissemination of uncommon practices in positive deviance studies for nutrition: A scoping review. [PDF]

BMC Nutr
Natukunda J, Choi S, Arita K, Ong KIC, Shibanuma A, Trivitayanurak W, Jimba M.   +6 more
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Using the Theoretical Domains Framework to Identify Barriers to and Enablers of Patient Telemedicine Services Use in China: Qualitative Study.

JMIR Hum Factors
Liu K, Yang Y, Song Z, Li H, Lyu Y, Zhang K, Wu X, Hou Z, Wang Y.   +8 more
europepmc   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Barriers and enablers affecting female participation in physical activity. [PDF]

Front Glob Womens Health
A'aqoulah A, Alonazi W, Kalmey F, Innab N, Abusaris R.   +4 more
europepmc   +1 more source

Enabling interdisciplinary research [PDF]

Nature Human Behaviour, 2017
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Enablers and barriers of e-learning utilising smart technologies in type 2 diabetes care for clinicians: a systematic review. [PDF]

BMJ Open
Alanazi MM, Fellas A, Bridge P, Acharya S, Santos D, Sculley D, Girones X, Coda A.   +7 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Translational Needs: Informing Tools to Close the Knowledge-to-Practice Gap in Suicide Prevention. [PDF]

Health Promot J Austr
Tran M, Stewart L, Cuenca J, Benson M, Reifels L.   +4 more
europepmc   +1 more source