Results 181 to 190 of about 15,943 (256)

30 Years of Enamel Matrix Derivative (EMD): Biological Foundations and Systematic Review With Meta‐Analyses Across Multiple Clinical Indications

open access: yesJournal of Periodontal Research, EarlyView.
EMD is one of the few biological agents with human histologic evidence supporting periodontal regeneration. This is reflected in improved clinical outcomes when used in regenerative surgery for intrabony defects. Despite its biological plausibility for broader therapeutic applications, further high‐quality randomized clinical trials are needed to ...
Richard J. Miron   +10 more
wiley   +1 more source

Retinoic Acid Excess Impairs Amelogenesis Inducing Enamel Defects. [PDF]

open access: yesFront Physiol, 2016
Morkmued S   +7 more
europepmc   +1 more source

Nanoparticles in Periodontology and Implant Dentistry: From Mechanisms to Clinical Applications

open access: yesJournal of Periodontal Research, EarlyView.
Nanotechnology holds significant promise in improving dental care, yet there is a need for more reliable clinical studies to validate its effectiveness and safety. ABSTRACT Recent advances in nanotechnology are reshaping the landscape of periodontology and implant dentistry, particularly through the application of nanoparticles (NPs).
Chun Xu   +4 more
wiley   +1 more source

Bone Grafts: Everything You Need to Know

open access: yesJournal of Periodontal Research, EarlyView.
This review classifies bone grafts (autograft, allograft, xenograft, synthetic) by source and osteogenic/inductive/conductive potential, linking material properties and mechanisms to clinical indications in periodontal and dental regeneration. Key challenges—limited osteoinduction, poor vascularisation, unbalanced resorption, handling difficulties, and
Håvard Jostein Haugen   +5 more
wiley   +1 more source

The Tunneled Coronally Advanced Flap (TCAF) for Root Coverage Procedures: Rationale, Indications, and a Novel Papilla‐Based Decision Tree

open access: yesJournal of Periodontal Research, EarlyView.
This technical report describes the clinical rationale for TCAF and introduces a papilla‐based decision tree to assist clinicians in selecting the most appropriate strategy (open vs. tunnel) for each individual papilla.
Lorenzo Tavelli, Shayan Barootchi
wiley   +1 more source

A Practical Guide to Evidence Synthesis: Meta‐Analysis, Network Meta‐Analysis, Meta‐Regressions and Beyond

open access: yesJournal of Periodontal Research, EarlyView.
This tutorial provides a clear and precise overview of pairwise and network meta‐analysis, including their core methodological assumptions. ABSTRACT Meta‐analysis has become an indispensable tool in medical and dental research, providing an estimate of treatment efficacy or harm by combining data from all relevant studies identified by a systematic ...
Yu‐Kang Tu   +4 more
wiley   +1 more source

Pharmacological Modulation of Nrf2 Signaling Regulates Oxidative Stress, Inflammation, and Alveolar Bone Loss in Experimental Periodontitis

open access: yesJournal of Periodontal Research, EarlyView.
Pharmacological activation of Nrf2 attenuated alveolar bone loss and protected periodontal tissues by reducing inflammation and oxidative stress, preserving collagen organization, and favoring bone homeostasis. Reversal of these effects by Nrf2 inhibition further supports Nrf2 signaling as a promising therapeutic target in periodontitis.
Vitória Bonan Costa   +8 more
wiley   +1 more source

Preoperative 3D Morphological Predictors of Bone Bridge Formation in Secondary Alveolar Bone Grafting: A CBCT Analysis

open access: yesOrthodontics &Craniofacial Research, EarlyView.
ABSTRACT Purpose To identify independent preoperative three‐dimensional (3D) morphological predictors for postoperative bone bridge formation in secondary alveolar bone grafting (SABG) using cone‐beam computed tomography (CBCT), and to propose an optimal surgical strategy based on these quantitative indicators.
Toshiro Kibe   +9 more
wiley   +1 more source

Root surface biomodification in periodontal therapy: Biological rationale and clinical applications

open access: yesPeriodontology 2000, EarlyView.
Abstract Regenerative periodontal therapy aims to form new cementum, periodontal ligament, and alveolar bone, all sealed by gingival tissue. The root surface acts as the wound margin during this regeneration process. Root surface biomodification (root conditioning/root decontamination), therefore, seems instrumental in promoting surface decontamination
Muhammad H. A. Saleh   +3 more
wiley   +1 more source

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