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Advances in viral encephalitis: Viral transmission, host immunity, and experimental animal models. [PDF]
Zool Res, 2023 Viral infections have led to many public health crises and pandemics in the last few centuries. Neurotropic virus infection-induced viral encephalitis (VE), especially the symptomatic inflammation of the meninges and brain parenchyma, has attracted ...
Yang D, Li XJ, Tu DZ, Li XL, Wei B.
europepmc +2 more sources
Rift Valley Fever Virus Encephalitis: Viral and Host Determinants of Pathogenesis. [PDF]
Annu Rev VirolRift Valley fever virus (RVFV) is a mosquito-borne virus endemic to Africa and the Middle East. RVFV infection can cause encephalitis, which is associated with significant morbidity and mortality.
Wilson LR, McElroy AK.
europepmc +2 more sources
Encyclopedia of the Neurological Sciences, 2014 Encephalitis is inflammation and swelling of the brain, often caused by an acute viral infection, or a para- or postinfectious phenomenon known as acute disseminated encephalomyelitis (ADEM).
L. Turtle, T. Solomon
europepmc +2 more sources
The Causes and Long-Term Consequences of Viral Encephalitis
Frontiers in Cellular Neuroscience, 2021 Reports regarding brain inflammation, known as encephalitis, have shown an increasing frequency during the past years. Encephalitis is a relevant concern to public health due to its high morbidity and mortality.
Karen Bohmwald +5 more
semanticscholar +3 more sources
The immunobiology of herpes simplex virus encephalitis and post-viral autoimmunity
Brain : a journal of neurology, 2023 Herpes simplex virus encephalitis (HSE) is the leading cause of non-epidemic encephalitis in the developed world and, despite antiviral therapy, mortality and morbidity is high.
J. Cleaver +6 more
semanticscholar +1 more source
Viral Encephalitis After Hematopoietic Cell Transplantation: A Systematic Review.
Transplantation and Cellular Therapy, 2023 BACKGROUND Viral encephalitis is a rare but serious complication after hematopoietic cell transplantation (HCT). The non-specific early signs and symptoms and rapid progression can make it difficult to diagnose and treat in a timely fashion ...
D. Toomey +4 more
semanticscholar +1 more source
Herpes Simplex Virus 1-Induced Ferroptosis Contributes to Viral Encephalitis
mBio, 2022 Ferroptosis is a nonapoptotic form of programmed cell death that contributes to different neurological inflammatory diseases. However, whether HSV-1 induces ferroptosis in the CNS and the role of ferroptosis in viral pathogenesis remain unclear. ABSTRACT
Xiqiu Xu +9 more
semanticscholar +1 more source
The roles of microglia in viral encephalitis: from sensome to therapeutic targeting
Cellular & Molecular Immunology, 2021 Viral encephalitis is a devastating disease with high mortality, and survivors often suffer from severe neurological complications. Microglia are innate immune cells of the central nervous system (CNS) parenchyma whose turnover is reliant on local ...
Chintan Chhatbar, M. Prinz
semanticscholar +1 more source
Beneficial and detrimental functions of microglia during viral encephalitis.
Trends in Neurosciences, 2021 Microglia are resident immune cells of the central nervous system (CNS) with multiple functions in health and disease. Their response during encephalitis depends on whether inflammation is triggered in a sterile or infectious manner, and in the latter ...
I. Waltl, U. Kalinke
semanticscholar +1 more source
Human viral encephalitis associated with suid herpesvirus 1
Neurological Sciences, 2021 Suid herpesvirus type 1 (SHV1) is a type of neurotropic virus able to infect various species. However, the clinical cases of human SHV1 encephalitis are still rarely reported, and the clinical characteristics, treatment, and prognosis of human SHV1 ...
Yi-Yi Zhou +6 more
semanticscholar +1 more source