Results 151 to 160 of about 70,458 (236)

A Phase I Study Evaluating Safety and Tolerability of Viral‐Specific T Cells Against BK‐Virus in Adult Kidney Transplant Recipients

open access: yesJournal of Medical Virology, Volume 97, Issue 4, April 2025.
ABSTRACT BK polyomavirus (BKPyV) poses a significant threat to kidney transplant recipients (KTR). Current management primarily involves reducing immunosuppression, which increases the risk of rejection. Cell‐based immunotherapy with virus‐specific T cells (VST) has emerged as an alternative approach for treating BKPyV in KTRs. This single‐center phase
Lucy Ptak   +8 more
wiley   +1 more source

Analysis of the Functional Role of TIMM29 in the Hepatitis B Virus Life Cycle

open access: yesMicrobiology and Immunology, Volume 69, Issue 4, Page 229-246, April 2025.
ABSTRACT Hepatitis B virus (HBV) causes chronic hepatitis B, which can progress to liver cirrhosis and hepatocellular carcinoma. HBV has complex interactions with various cell organelles and proteins that ensure effective progeny virus production. We previously reported that a mitochondrial protein, TIMM29, should regulate the HBV life cycle through ...
Limia Abueldahab   +6 more
wiley   +1 more source

Monkeypox Virus: WHO's Second Public Health Emergency of International Concern Within 2 Years

open access: yesMicrobial Biotechnology, Volume 18, Issue 4, April 2025.
The figure shows examples of zoonotic diseases and their affected populations. The red arrows indicate the path of monkeypox virus infections first from a wild animal reservoir (rodents, squirrels) as a zoonosis mostly to children in central and west Africa, followed by the 2022/3 epidemic with human‐to‐human transmission in men having sex with men and
Harald Brüssow
wiley   +1 more source

Diagnosing and Preventing Q Fever in Regional New South Wales, Australia—A Qualitative Exploration of Perspectives of General Practitioners

open access: yesAustralian Journal of Rural Health, Volume 33, Issue 2, April 2025.
ABSTRACT Objective To qualitatively explore the perceptions of general practitioners in regional New South Wales, Australia, on diagnosing, managing and preventing Q fever. Setting Q fever is a prevalent zoonosis in regional New South Wales, but diagnosis may be missed as patients have symptoms similar to influenza or COVID.
Sachith Maduranga   +10 more
wiley   +1 more source

The Omics Landscape of Long COVID—A Comprehensive Systematic Review to Advance Biomarker, Target and Drug Discovery

open access: yesAllergy, Volume 80, Issue 4, Page 932-948, April 2025.
ABSTRACT An estimated 10% of coronavirus disease (COVID‐19) survivors suffer from persisting symptoms referred to as long COVID (LC), a condition for which approved treatment options are still lacking. This systematic review (PROSPERO: CRD42024499281) aimed to explore the pathophysiological mechanisms underlying LC and potential treatable traits across
Nadia Baalbaki   +6 more
wiley   +1 more source

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