Enterovirus A‐71 Associated Parainfectious Movement Disorders in Children
Movement Disorders Clinical Practice, EarlyView.Abstract Background Pediatric movement disorders can be challenging to characterize, given the phenotypic complexity and broad differential diagnosis. While genetic tests are often part of the diagnostic work‐up, it is important to consider acquired causes, which may require specific investigations.
Suus A. M. van Noort +6 more
wiley +1 more source
The Hsp90β Isoform: An Attractive Target for Drug Development
Medicinal Research Reviews, EarlyView.ABSTRACT The beta isoform of 90 kDa heat shock protein (Hsp90β) plays a critical role in maintaining cellular proteostasis by assisting in the folding and refolding of proteins, which is essential for both normal cellular function and stress response.
Subhabrata Chaudhury +2 more
wiley +1 more source
The Antiviral Activity of Polyphenols
Molecular Nutrition &Food Research, EarlyView.Polyphenols demonstrate remarkable antiviral properties by effectively disrupting multiple biochemical processes essential for viral replication. ABSTRACT Polyphenols are secondary metabolites produced by a large variety of plants. These compounds that comprise the class of phenolic acids, stilbenes, lignans, coumarins, flavonoids, and tannins have a ...
Markus Burkard +5 more
wiley +1 more source
CCR2 Inhibition Reduces Neurotoxic Microglia Activation Phenotype After Japanese Encephalitis Viral Infection. [PDF]
Front Cell Neurosci, 2020 Singh S, Singh G, Tiwari S, Kumar A.
europepmc +1 more source
Review of Human Coronaviruses and Other Respiratory Viruses and their Neurological Impact on the Central Nervous System [PDF]
, 2020 Comprehensive reporting shows that some pathogens, including COVID-19, influenza A and SARS-CoV have sometimes caused pandemics and were linked to more serious diseases and death.
Haider, Monica, Thomas, M.D., Haider
core
Frequency of Guillain‐Barré Syndrome During the COVID‐19 Pandemic: A Multicenter Study
Muscle &Nerve, EarlyView.ABSTRACT Introduction/Aims The incidence of Guillain‐Barré syndrome (GBS) during the COVID‐19 pandemic varies according to country. We investigated the changes in the number of patients with GBS and their characteristics who were reported in Tokyo in 2020 at the beginning of the COVID‐19 pandemic, compared to those two years prior.
Toshiyuki Hayashi +14 more
wiley +1 more source
Clinical and Serological Findings of Madariaga and Venezuelan Equine Encephalitis Viral Infections: A Follow-up Study 5 Years After an Outbreak in Panama. [PDF]
Open Forum Infect Dis, 2020 Carrera JP +14 more
europepmc +1 more source
A comprehensive review on adaptive plasticity and recovery mechanisms post‐acquired brain injury
Neuroprotection, EarlyView.This figure illustrates the dynamic process of neurogenesis following brain injury, focusing on the roles of neural stem and progenitor cells at the injury site. Key mechanisms include axonal sprouting, synaptogenesis, dendritic remodeling, and brain‐derived neurotrophic factor signaling via TrkB receptors.
Ravi Kumar Rajan
wiley +1 more source
Physico-chemical requirements and kinetics of membrane fusion of flavivirus-like particles. [PDF]
, 2015 Flaviviruses deliver their RNA genome into the host-cell cytoplasm by fusing their lipid envelope with a cellular membrane. Expression of the flavivirus pre-membrane and envelope glycoprotein genes in the absence of other viral genes results in the ...
core +1 more source
ChemistryOpen, EarlyView.A library of easily synthesizable CAPE analogs was screened in silico against the dengue virus envelope protein. Compound LQM778 showed stable binding and promising inhibitory potential. This study highlights LQM778 as a candidate for future in vitro validation and structural optimization toward accessible antiviral agents against dengue.
Luis Alfonso Cárdenas‐Granados +9 more
wiley +1 more source