Results 181 to 190 of about 663,455 (279)

Dengue Virus Molecular Targets and Antiviral Drug Development: Advances, Challenges and Therapeutic Perspectives

open access: yesChemistrySelect, Volume 11, Issue 33, 1 September 2026.
This narrative review analyzes DENV molecular targets, including structural proteins (C, prM/M, E), non‐structural components (NS1NS5), and host factors, alongside small‐molecule candidates in preclinical and clinical phases. Owing to high structural conservation, the NS2B‐NS3 protease and NS5 (RdRp/MTase) remain primary drug discovery focuses, while ...
Aryane Lucia da Silva Aguiar De Oliveira   +8 more
wiley   +1 more source

Metabolic Signatures and Diagnostic Strategies for Different Types of Encephalitis. [PDF]

open access: yesCNS Neurosci Ther
Cui Y   +10 more
europepmc   +1 more source

Molecular and Serological Screening of West Nile and Usutu Virus in Birds and Humans: A Sentinel Study in Finland

open access: yesVeterinary Medicine and Science, Volume 12, Issue 5, September 2026.
We developed sensitive real‐time PCR assays for West Nile virus and Usutu virus to screen bird and human samples in Finland. Although no positive samples were detected, active migratory flyways and recent cases in neighbouring countries highlight the risk of future introduction and the need for continued surveillance.
Ruut Joensuu   +6 more
wiley   +1 more source

What drives hateful tweets to go viral? Threat perception and Twitter engagement: The case of the COVID‐19 pandemic

open access: yesAsian Journal of Social Psychology, Volume 29, Issue 3, September 2026.
Abstract Drawing on Intergroup Threat Theory as an analytical framework, this study analyses pandemic‐driven Sinophobic tweets to examine how threat‐laden language influences user engagement through computational text analysis. Findings showed that those conveying ideological threats generated higher engagement, whereas those involving mixed threat ...
Hyejin Kim, Thyago Mota, Sanga Song
wiley   +1 more source

Melioidosis in companion animals: Analysis of 45 Australian cases (24 dogs; 21 cats) from 1997 to 2025 and a brief review of the animal and human literature

open access: yesAustralian Veterinary Journal, Volume 104, Issue 9, Page 563-580, September 2026.
Objective To report 45 cases of melioidosis in dogs and cats from northern Australia and analyse trends in epidemiology, clinical presentation, pathogenesis and response to treatment over a 27‐year period. Design Retrospective and prospective analysis of clinical records.
K Lee   +6 more
wiley   +1 more source

Herpes simplex virus encephalitis following acute brain injury: illustrative cases. [PDF]

open access: yesJ Neurosurg Case Lessons
Shay AK   +7 more
europepmc   +1 more source

When to consider an inborn error of immunity: clues for physicians

open access: yesInternal Medicine Journal, Volume 56, Issue 9, Page 1488-1499, September 2026.
Abstract The term inborn errors of immunity (IEIs) refers to the rapidly expanding group of genetic disorders causing dysregulation of the immune system. With improved genetic testing in recent years, the number of defined IEIs and their range of phenotypic presentations has grown vastly, with more than 550 IEIs now described.
Meera Thangarajah, Lucinda J. Berglund
wiley   +1 more source

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