Human Cyclophilins—An Emerging Class of Drug Targets
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova +3 more
wiley +1 more source
Integrated Transcriptomic and Machine Learning Analysis Reveals Immune-Related Regulatory Networks in Anti-NMDAR Encephalitis. [PDF]
Fang K, Li X, Wang J.
europepmc +1 more source
Cancer patients might be relatively more prone to zolpidem withdrawal delirium because of the possible Blood–Brain Barrier dysfunction derived from anticancer drug treatment or cancer. Oncologists and liaison psychiatrists need to prevent and detect zolpidem withdrawal delirium, because it may be difficult to manage withdrawal delirium with severe ...
Junji Yamaguchi +6 more
wiley +1 more source
Real-World Evaluation of the BioFire FilmArray ME Panel: Diagnostic Accuracy and Clinical Utility. [PDF]
Erinmez M +4 more
europepmc +1 more source
Prolonged Anti‐Zic4 Antibody–Positive Cerebellar Degeneration Following COVID‐19 Infection
Serial MRI and SPECT revealed progressive cerebellar atrophy and worsening hypoperfusion over 2 years, despite partial clinical stabilization. These findings highlight radiological progression that exceeds symptom severity in post‐COVID anti‐Zic4 antibody–associated cerebellar degeneration.
Risa Suzuki‐Yamamoto +6 more
wiley +1 more source
A rare case of breakthrough tick-borne encephalitis in early adolescence after vaccination with four doses of TBE vaccine. [PDF]
Morgardt S +4 more
europepmc +1 more source
MRI as a key tool in presumptive antemortem diagnosis of rabies: A case report. [PDF]
Tuji EF +4 more
europepmc +1 more source
Case Report: Anti-neural cell adhesion molecule 1 antibody-positive encephalitis presenting with schizophrenia-like symptoms and an ovarian teratoma. [PDF]
Yamanaka N +9 more
europepmc +1 more source

