Results 51 to 60 of about 315,809 (313)

Cloning, expression, purification, and structural modeling of the Chandipura virus matrix protein

FEBS Open Bio, EarlyView.
This research protocol offers a guide for the cloning, expression, and purification of the Chandipura virus matrix protein using E. coli. It also includes a step‐by‐step procedure for cloning, expressing, and conducting fluorescence imaging of GFP‐fused Chandipura virus matrix protein in mammalian cell lines.
Mariana Grieben
wiley   +1 more source

Gut microbiome diversity in a febrile seizure mouse model [PDF]

Encephalitis
Purpose Febrile seizures at a young age can provoke late-onset temporal lobe epilepsy. Since recent evidence has suggested that the gut microbiome affects central nervous system pathology across the blood-brain barrier, we hypothesized that febrile ...
Yongmoo Kim, Yoonhyuk Jang, Yong-Won Shin, Daejong Jeon, Jung-seok Yoo, Dong-Kyu Park, Han Sang Lee, Seon-Jae Ahn, Kyung-Il Park, Keun-Hwa Jung, Soon-Tae Lee, Sang Kun Lee, Kon Chu   +12 more
doaj   +1 more source

A Key to Container-Breeding Mosquitoes of Michigan (Diptera: Cllllcidae), With Notes on Their Biology [PDF]

, 2017
An illustrated key to larvae and notes on the biology of container-breeding mosquitoes of Michigan are presented. Two species included in the key. Aedes aegypti and Aedes albopictus.
Merritt, Richard W, Wilmot, Thomas R, Zeller, Deborah S   +2 more
core   +3 more sources

CSF Mitochondrial DNA: Biomarker of Body Composition and Energy Metabolism in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebrospinal fluid (CSF) cell‐free mitochondrial DNA (cf‐mtDNA) is a potential biomarker for Parkinson's disease (PD), but its clinical relevance remains unclear. We investigated associations between CSF cf‐mtDNA levels, body composition, nutritional status, and metabolic biomarkers in PD. Methods CSF cf‐mtDNA levels, defined as the
Yasuaki Mizutani, Tsuyoshi Nakai, Yasuhiro Maeda, Reiko Ohdake, Atsuhiro Higashi, Toshiki Maeda, Ryunosuke Nagao, Sayuri Shima, Kazuya Kawabata, Akihiro Ueda, Mizuki Ito, Hirohisa Watanabe   +11 more
wiley   +1 more source

Integrating patient and public involvement during the COVID-19 pandemic: lessons from COVID-clinical neuroscience study

Research Involvement and Engagement
Background The COVID-19 Clinical Neuroscience Study (COVID-CNS) was a large UK research initiative investigating the clinical features, outcomes and biological mechanisms behind neurological and psychiatric complications from COVID-19.
Praveen Prathapan, Mark A. Ellul, Emma Collins, Stephen McKeever, Ava Easton, Benedict D. Michael   +5 more
doaj   +1 more source

Impact of standardized electroencephalography terminology education among early-career neurologists in Korea: a single-group pretest–posttest study [PDF]

Encephalitis
Purpose This study evaluated the effectiveness of implementing standardized electroencephalography (EEG) terminology and education on improving interpretation skills among non-English speakers.
Kyung-Il Park, Sang Bin Hong, Hansang Lee   +2 more
doaj   +1 more source

Analysis of Soluble Interleukin‐2 Receptor as a Prognostic Biomarker in NMOSD and MOGAD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Soluble interleukin‐2 receptor (sIL‐2R) is a biomarker for T cell activity. T cells are involved in neuromyelitis optica spectrum disorders (NMOSD) and myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) pathogenesis. However, sIL‐2R has so far not been evaluated in these conditions.
Philipp Klyscz, Carolin Otto, Klemens Ruprecht, Susanna Asseyer, Hannes Ole Tiedt, Christian Meisel, Judith Bellmann‐Strobl, Friedemann Paul, Patrick Schindler   +8 more
wiley   +1 more source

MODELLING OF HEPATITIS E IN MINI-PIGS

Журнал микробиологии, эпидемиологии и иммунобиологии, 2017
Aim. Experimental reproduction of HEV-infection in mini-pigs and comparative analysis of virological and immunological characteristics of experimental infection. Materials and methods.
S. A. Gulyaev, I. A. Potemkin, V. S. Kichatova, A. A. Karlsen, O. V. Isaeva, T. V. Guiyaeva, M. A. Vannus, I. V. Gordeichuk, K. K. Kyuregyan, M. I. Mikhailov   +9 more
doaj   +1 more source

Modeling viral infectious diseases and development of antiviral therapies using human induced pluripotent stem cell-derived systems [PDF]

, 2015
The recent biotechnology breakthrough of cell reprogramming and generation of induced pluripotent stem cells (iPSCs), which has revolutionized the approaches to study the mechanisms of human diseases and to test new drugs, can be exploited to generate ...
Barzon, Luisa, Berto, Alessandro, Desole, Giovanna, Pacenti, Monia, Palu', Giorgio, Sinigaglia, Alessandro, Trevisan, Marta   +6 more
core   +2 more sources

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin, Sang Bin Hong, Yong Woo Shin, Inpyeong Hwang, Jaeseong Oh, Jihyeon Choi, Narae Kim, Jangsup Moon, Keun‐Hwa Jung, Kyung‐Il Park, Ki‐Young Jung, Kon Chu, Sang Kun Lee   +12 more
wiley   +1 more source