Results 21 to 30 of about 58,138 (49)

Changing Geographic Distribution of Japanese Encephalitis Virus Genotypes, 1935-2017.

Vector Borne and Zoonotic Diseases, 2019
Japanese encephalitis virus (JEV) is a representative virus of the JEV serogroup in genus Flavivirus, family Flaviviridae. JEV is a mosquito-borne virus that causes Japanese encephalitis (JE), one of the most severe viral encephalitis diseases in the ...
Xiao-yan Gao, Hong Liu, Xiaolong Li, S. Fu, Lei Cao, Nan Shao, Weijia Zhang, Qianying Wang, Zhi Lu, W. Lei, Ying He, Yu-xi Cao, Huanyu Wang, G. Liang   +13 more
semanticscholar   +1 more source

Japanese Encephalitis Virus Induces Apoptosis and Encephalitis by Activating the PERK Pathway

Journal of Virology, 2019
Japanese encephalitis virus (JEV) infection triggers endoplasmic reticulum (ER) stress and neuron apoptosis. ER stress sensor protein kinase R-like endoplasmic reticulum kinase (PERK) has been reported to induce apoptosis under acute or prolonged ER ...
Qianruo Wang, Xiu Xin, Ting Wang, Jiawu Wan, Yangtao Ou, Zibing Yang, Q. Yu, Liting Zhu, Yunli Guo, Yinsheng Wu, Zhen Ding, Yan-ni Zhang, Z. Pan, Yuxin Tang, Shanshan Li, Lingbao Kong   +15 more
semanticscholar   +1 more source

Japanese encephalitis virus neuropenetrance is driven by mast cell chymase

Nature Communications, 2019
Japanese encephalitis virus (JEV) is a leading cause of viral encephalitis. However, the mechanisms of JEV penetration of the blood-brain-barrier (BBB) remain poorly understood.
J. T. Hsieh, Abhay P. S. Rathore, G. Soundarajan, A. S. St. John   +3 more
semanticscholar   +1 more source

How Central Is the Domestic Pig in the Epidemiological Cycle of Japanese Encephalitis Virus? A Review of Scientific Evidence and Implications for Disease Control

Viruses, 2019
Despite the existence of human vaccines, Japanese encephalitis (JE) remains the leading cause of human encephalitis in Asia. Pigs are described as the main amplifying host, but their role in JE epidemiology needs to be reassessed in order to identify and
Héléna Ladreyt, B. Durand, P. Dussart, V. Chevalier   +3 more
semanticscholar   +1 more source

Virus Like Particles (VLP) as multivalent vaccine candidate against Chikungunya, Japanese Encephalitis, Yellow Fever and Zika Virus

Scientific Reports, 2020
Mosquito borne viral diseases are an emerging threat as evident from the recent outbreak of Zika virus (ZIKV) as well as repeated outbreaks of Chikungunya (CHIKV), Yellow fever (YFV) and Japanese encephalitis (JEV) virus in different geographical regions.
H. Garg, Tugba Mehmetoglu-Gurbuz, A. Joshi   +2 more
semanticscholar   +1 more source

Inhibition of Japanese encephalitis virus infection by the host zinc-finger antiviral protein

PLoS Pathogens, 2018
CCCH-type zinc-finger antiviral protein (ZAP) is a host factor that restricts the infection of many viruses mainly through RNA degradation, translation inhibition and innate immune responses.
Hsin-Ping Chiu, Han Chiu, C. Yang, Yi-Ling Lee, Feng‐Lan Chiu, H. Kuo, Ren-Jye Lin, Yi-Ling Lin   +7 more
semanticscholar   +1 more source

Japanese Encephalitis Virus in Australia: From Known Known to Known Unknown

Tropical Medicine and Infectious Disease, 2019
Japanese encephalitis virus (JEV) is a major cause of neurological disease in Asia. It is a zoonotic flavivirus transmitted between water birds and/or pigs by Culex mosquitoes; humans are dead-end hosts.
A. F. van den Hurk, A. Pyke, J. Mackenzie, Sonja Hall-Mendelin, S. Ritchie   +4 more
semanticscholar   +1 more source

Crystal Structure of the Japanese Encephalitis Virus Capsid Protein

Viruses, 2019
Japanese encephalitis (JE) is inflammation and swelling of the brain caused by the JE virus (JEV), a mosquito-borne member of the Flavivirus family. There are around 68,000 JE cases worldwide each year, many of which result in permanent brain damage and ...
T. Poonsiri, G. Wright, T. Solomon, S. Antonyuk   +3 more
semanticscholar   +1 more source

Early Events in Japanese Encephalitis Virus Infection: Viral Entry

Pathogens, 2018
Japanese encephalitis virus (JEV), a mosquito-borne zoonotic flavivirus, is an enveloped positive-strand RNA virus that can cause a spectrum of clinical manifestations, ranging from mild febrile illness to severe neuroinvasive disease.
Sang-Im Yun, Young-Min Lee
semanticscholar   +1 more source

North American domestic pigs are susceptible to experimental infection with Japanese encephalitis virus

Scientific Reports, 2018
Japanese encephalitis virus (JEV) is a mosquito-borne flavivirus that is capable of causing encephalitic diseases in children. While humans can succumb to severe disease, the transmission cycle is maintained by viremic birds and pigs in endemic regions ...
So Lee Park, Yan-Jang S. Huang, A. C. Lyons, Victoria B. Ayers, S. Hettenbach, D. S. McVey, Kenneth R. Burton, S. Higgs, D. Vanlandingham   +8 more
semanticscholar   +1 more source