Results 41 to 50 of about 27,872 (237)

Forecasting median and mode dates of prevalence of Japanese encephalitis patients by electronic computer (epidemiological studies on Japanese encephalitis, 31)

, 1970
For the purpose of forecasting the prevalence ofJapanese encephalitis in Japan, we tried to find out the correlation of factors between median and mode dates of epidemic time curve of prevalence on one hand, and average atmospheric temperatures of ...
Ogata, Masana, Osaki, Hirokazu
core   +1 more source

Lethal Encephalitis in Seals with Japanese Encephalitis Virus Infection, China, 2017

Emerging Infectious Diseases, 2019
We isolated Japanese encephalitis virus (JEV) from brain samples of 2 seals with lethal encephalitis at Weihai Aquarium, Weihai, China, in 2017. We confirmed our findings by immunohistochemical staining and electron microscopy.
Xiangdong Li, Mingming Qiao, Xiaoyu Deng, Xi Chen, Shengyong Sun, Qian Zhang, Wenjie Zhang, Feifei Tan, Zhe Sun, Xizhao Chen, Ming Sun, Kegong Tian   +11 more
doaj   +1 more source

Multiple antiviral activities of the antimalarial and anti-hepatitis C drug candidates N-89 and N-251

Biochemistry and Biophysics Reports, 2018
The chemically synthesized endoperoxide compound N-89 and its derivative N-251 were shown to have potent antimalarial activity. We previously demonstrated that N-89 and N-251 potently inhibited the RNA replication of hepatitis C virus (HCV), which ...
Youki Ueda, Weilin Gu, Hiromichi Dansako, Hye-Sook Kim, Sayaka Yoshizaki, Nobuaki Okumura, Tomohiro Ishikawa, Hironori Nishitsuji, Fumihiro Kato, Takayuki Hishiki, Shinya Satoh, Koji Ishii, Michiaki Masuda, Kunitada Shimotohno, Masanori Ikeda, Nobuyuki Kato   +15 more
doaj   +1 more source

Isolation of saint louis encephalitis virus from a horse with neurological disease in Brazil. [PDF]

PLoS Neglected Tropical Diseases, 2013
St. Louis encephalitis virus (SLEV) is a causative agent of encephalitis in humans in the Western hemisphere. SLEV is a positive-sense RNA virus that belongs to the Flavivirus genus, which includes West Nile encephalitis virus, Japanese encephalitis ...
Roberta Rosa, Erica Azevedo Costa, Rafael Elias Marques, Taismara Simas Oliveira, Ronaldo Furtini, Maria Rosa Quaresma Bomfim, Mauro Martins Teixeira, Tatiane Alves Paixão, Renato Lima Santos   +8 more
doaj   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Arbovirus and seizures

Acta Epileptologica, 2020
The high prevalence and spread of arthropod-borne viruses (arboviruses) make them an important cause of viral encephalitis in humans. Most epidemic viral encephalitides have an etiology associated with arboviruses. Among various arboviruses, the Japanese
Mingrui Zheng, Shichuo Li, R. Edward Hogan, Meihua Yang   +3 more
doaj   +1 more source

Comment on van den Hurk et al. The Emergence of Japanese Encephalitis Virus in Australia in 2022: Existing Knowledge of Mosquito Vectors. Viruses 2022, 14, 1208

Viruses, 2023
I read with interest the article “The Emergence of Japanese Encephalitis Virus in Australia in 2022: Existing Knowledge of Mosquito Vectors” [...]
Michelle Nicole Brinkhoff
doaj   +1 more source

The Host Cell Factor Phosphatase‐2A Subunit PR130 Restricts Replication of Herpes Simplex Virus Type‐1

Advanced Science, EarlyView.
Molecular, genetic, virological, and biochemical analysis in combination with global proteome and phosphoproteome profiling and functional assays were applied to study the role of PR130 in the context of HSV‐1 replication. The observations reveal that host‐intrinsic mechanisms regulate HSV‐1 replication and highlight PR130 as a susceptibility factor of
Johannes Jungwirth, Christoph F. Jacob, Alexandra Nguyen, Mandy Beyer, Andreas O. Mieland, Mario Dejung, Jia‐Xuan Chen, Walburgis Brenner, Christina Ehrhardt, Andreas Henke, Oliver H. Krämer   +10 more
wiley   +1 more source

Minocycline for management of Japanese encephalitis: A case report

Journal of Vector Borne Diseases
Japanese encephalitis virus infection manifests as acute encephalitis syndrome leading to significant neurological disability with estimated incidence around 85,000 cases per year and case fatality rate of 30%.
Naveenraj Palaniswamy, PM Azarudheen, Syam Unnikrishnan   +2 more
doaj   +1 more source

RNF138‐Mediated Ubiquitination and Degradation of NS5 Restricts Tick‐Borne Encephalitis Virus Infection

Advanced Science, EarlyView.
Host‐specific compatibility between RNF138‐like proteins and flavivirus NS5 determines NS5 stability. Mammalian RNF138 but not arthropod homologs recognizes and induces conserved NS5/RdRp K48‐linked ubiquitination and proteasomal degradation, thereby restricting viral replication. Ectopic RNF138 in mice attenuates TBEV‐induced pathogenesis. (Created in
Jialiang Sun, Weijing Yang, Hao Zhou, Shuai Li, Xin Jiang, Jianyang Gu, Wenyan Zhang   +6 more
wiley   +1 more source