Results 31 to 40 of about 20,956 (131)

Physico-chemical requirements and kinetics of membrane fusion of flavivirus-like particles. [PDF]

, 2015
Flaviviruses deliver their RNA genome into the host-cell cytoplasm by fusing their lipid envelope with a cellular membrane. Expression of the flavivirus pre-membrane and envelope glycoprotein genes in the absence of other viral genes results in the ...

core   +1 more source

Acute encephalitis syndrome surveillance, Kushinagar district, Uttar Pradesh, India, 2011-2012 [PDF]

, 2013
In India, quality surveillance for acute encephalitis syndrome (AES), including laboratory testing, is necessary for understanding the epidemiology and etiology of AES, planning interventions, and developing policy.
Arunachalam, Beig, Bhatt, Elizabeth T. Rogawski, German RR, Lee LM, Horan JM, Milstein RL, Pertowski CA, Waller MN, Hills, Karmarkar, Kumar, Lewthwaite, Manish Kakkar, Parida, Roy, Sampath K. Krishnan, Samuel, Sanjay Chaturvedi, Sapkal, Sarkari, Saxena, Shaikh Shah Hossain, Syed Shahid Abbas, Tapan N. Dhole   +20 more
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Allosteric Regulation of RNA Affinity by Motif V‐VI Coupling in West Nile Virus NS3 Helicase

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The rise of flaviviral diseases, including West Nile virus (WNV), presents a growing threat to global public health and underscores the urgent need for new therapeutic strategies. The non‐structural protein 3 helicase (NS3h) of the Orthoflavivirus genus, including WNV, is essential for viral replication and a promising antiviral target ...
Priti Roy, Martin McCullagh
wiley   +1 more source

Emergence or improved detection of Japanese encephalitis virus in the Himalayan highlands? [PDF]

, 2016
The emergence of Japanese encephalitis virus (JEV) in the Himalayan highlands is of significant veterinary and public health concern and may be related to climate warming and anthropogenic landscape change, or simply improved surveillance. To investigate
Barker, Christopher M, Baylis, Matthew, Caminade, Cyril, Impoinvil, Daniel E, Joshi, Bhoj R, Pant, Ganesh R, Rayamajhi, Ajit, Reisen, William K   +7 more
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Tick‐Borne Encephalitis (TBE) Vaccine in the National Immunisation Programme—For Whom, When and Where?

Acta Paediatrica, EarlyView.
ABSTRACT The incidence of Tick‐borne encephalitis (TBE) cases has increased. The presumed location of transmission of Tick‐borne encephalitis virus (TBEV) has been expanding increasingly in the western parts of Europe during the past decade. There has also been an increased incidence of surveillance‐reported TBE cases in southern Sweden and southern ...
H. H. Askling, D. Zavadska
wiley   +1 more source

Zika virus tropism and interactions in myelinating neural cell cultures: CNS cells and myelin are preferentially affected [PDF]

, 2017
The recent global outbreak of Zika virus (ZIKV) infection has been linked to severe neurological disorders affecting the peripheral and central nervous systems (PNS and CNS, respectively). The pathobiology underlying these diverse clinical phenotypes are
Barnett, Susan C., Barrie, Jennifer A., Brennan, Benjamin, Cumberworth, Stephanie L., Cunningham, Madeleine E., de Oliveira França, Rafael Freitas, Edgar, Julia M., Gomes de Figueiredo, Daniely Paulino, Kohl, Alain, Linington, Christopher, Pena, Lindomar J., Schultz, Verena, Wilder-Smith, Adrian J., Willison, Hugh J.   +13 more
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Shrubs and trees as natural insect protection for grazing animals in Switzerland and the alpine region: A systematic review of in vitro, in vivo and clinical trials Sträucher und Bäume als natürlicher Insektenschutz für Weidetiere in der Schweiz und im Alpenraum: Eine systematische Literaturübersicht über in vitro‐, in vivo‐ und klinische Studien

Medical and Veterinary Entomology, EarlyView.
Biting or irritating insects are a threat to the health and welfare of grazing animals. This systematic review reveals that several shrubs and bushes growing in the alpine area have insecticidal, insect‐repellent and/or attractant properties. The alder Alnus glutinosa, juniper Juniperus communis, spruce Picea abies and walnut Juglans regia are ...
Theresa Schlittenlacher, Sofie Egli, Michael Walkenhorst, Veronika Maurer   +3 more
wiley   +1 more source

Temperature-sensitive mutants of Japanese encephalitis virus [PDF]

Journal of Virology, 1985
Ten stable temperature-sensitive mutants of Japanese encephalitis virus were isolated after mutagenesis by growth of cloned wild-type virus in the presence of the nucleic acid precursor analogs 5-fluorouracil and 5-azacytidine. Mutants were selected which grew at least 100-fold better at 33 degrees C than at 41 degrees C.
P S, Eastman, C D, Blair
openaire   +2 more sources

Zoonosis emergence linked to agricultural intensification and environmental change [PDF]

, 2013
A systematic review was conducted by a multidisciplinary team to analyze qualitatively best available scientific evidence on the effect of agricultural intensification and environmental changes on the risk of zoonoses for which there are epidemiological ...
Artois, B. A. Jones, Belotto, Boureau, Brown, Childs, Chomel, Chua, Cleaveland, Cutler, D. Grace, D. McKeever, D. U. Pfeiffer, Daszak, Drew, Drexler, Ducheyne, Dugan, Epstein, Epstein, F. Mutua, Fevre, Field, Gilchrist, Goldberg, Graham, Harper, Hayman, Hsu, Irvine, J. McDermott, J. Rushton, J. Young, Jones, Keesing, Landolt, Lehle, Leibler, Leroy, M. Y. Said, Mas-Coma, Mathews, Maudlin, McMichael, Morse, Pepin, Pfeffer, R. Kock, Reynes, Rwego, S. Alonso, Sendow, Sims, Springbett, Tricco, van den Hurk, Vora, Wacharapluesadee, Woolhouse, Yob   +59 more
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Immune involvement in neuropsychiatric disorders: Insights from single‐cell transcriptomic studies

Psychiatry and Clinical Neurosciences, EarlyView.
Neuropsychiatric disorders pose profound challenges to both research and treatment, largely due to their clinical heterogeneity and the limited understanding of their underlying biological mechanisms. While bulk RNA sequencing (bulk RNA‐seq) has been widely used to study gene expression, it cannot resolve cell‐type‐specific signals or detect rare ...
Tsutomu Takeda, Michihiro Toritsuka, Hiroto Tamakoshi, Nakao Iwata, Manabu Makinodan   +4 more
wiley   +1 more source