Results 131 to 140 of about 30,980 (265)
Suppression of Type I Interferon Signaling by Flavivirus NS5. [PDF]
, 2018 Type I interferon (IFN-I) is the first line of mammalian host defense against viral infection. To counteract this, the flaviviruses, like other viruses, have encoded a variety of antagonists, and use a multi-layered molecular defense strategy to ...
Hai, Rong +3 more
core
Attenuation of Tick-Borne Encephalitis Virus Using Large-Scale Random Codon Re-encoding
PLoS Pathogens, 2015 Large-scale codon re-encoding (i.e. introduction of a large number of synonymous mutations) is a novel method of generating attenuated viruses. Here, it was applied to the pathogenic flavivirus, tick-borne encephalitis virus (TBEV) which causes febrile ...
L. de Fabritus +4 more
semanticscholar +1 more source
Serologic Evidence of Powassan Virus Infection in Patients with Suspected Lyme Disease
Emerging Infectious Diseases, 2017 Powassan virus (POWV) lineage II is an emerging tickborne flavivirus with an unknown seroprevalence in humans. In a Lyme disease–endemic area, we examined the seroreactivity to POWV in 2 patient cohorts and described the clinical features of the POWV ...
Holly M. Frost +8 more
doaj +1 more source
[Chromatography of formalin-inactivated tick-borne encephalitis viruses on macroporous glass].
Voprosy virusologii, 1981 The results of further development of methods for chromatographic concentration and purification of tick-borne encephalitis virus on columns with porous glass using formalin-inactivated virus suspensions are presented. The method of adsorption chromatography on porous glass under optimal conditions concentrates inactivated TBE virus 20-40-fold with ...
L B, El'bert +4 more
openaire +1 more source
Ticks and Tick-Borne DiseasesTicks transmit diverse viral pathogens to hosts during blood-feeding via saliva secretion. This study characterized viral compositions in salivary glands and saliva from adults of four tick species (Ixodes persulcatus, Rhipicephalus microplus ...
Jun Ni +9 more
doaj +1 more source
Irreversible furin cleavage site exposure renders immature tick-borne flaviviruses fully infectious
Nature CommunicationsFlavivirus assembly is driven by the envelope glycoproteins pre-membrane (prM) and envelope (E) in the neutral pH environment of the endoplasmic reticulum.
Jiří Holoubek +16 more
doaj +1 more source
Antioxidants as Potential Antiviral Agents for Flavivirus Infections
Антибиотики и Химиотерапия, 2020 The review considers potential opportunities of certain antioxidants as antiviral agents for flavivirus infections. Currently flavivirus infections represent a significant public health problem for various regions of the world, since they result in high ...
N. V. Krylova +2 more
doaj
Проблемы особо опасных инфекцийThe circulation of a rather wide range of pathogens of natural-focal infectious diseases transmitted by ticks was detected in West Africa at different points of time: Borrelia, Rickettsia, Coxiella, Crimean-Congo hemorrhagic fever (CCHF), Bhanja, and ...
E. V. Naidenova +9 more
doaj +1 more source