Results 41 to 50 of about 29,601 (260)

Crystal structure of a tick-borne flavivirus RNA-dependent RNA polymerase suggests a host adaptation hotspot in RNA viruses

open access: yesNucleic Acids Research, 2021
The RNA-dependent RNA polymerases (RdRPs) encoded by RNA viruses represent a unique class of nucleic acid polymerases. RdRPs are essential in virus life cycle due to their central role in viral genome replication/transcription processes.
Jieyu Yang   +8 more
semanticscholar   +1 more source

Extensive diversity of RNA viruses in ticks revealed by metagenomics in northeastern China.

open access: yesPLoS Neglected Tropical Diseases, 2022
BackgroundTicks act as important vectors of infectious agents, and several emerging tick-borne viruses have recently been identified to be associated with human diseases in northeastern China.
Ziyan Liu   +16 more
doaj   +1 more source

Efficient assembly and secretion of recombinant subviral particles of the four dengue serotypes using native prM and E proteins. [PDF]

open access: yes, 2009
© 2009 Wang et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited ...
Béatrice Nal   +10 more
core   +8 more sources

The Role of IFITM Proteins in Tick-Borne Encephalitis Virus Infection

open access: yesJournal of Virology, 2021
TBEV infection may result in encephalitis, chronic illness, or death. TBEV is endemic in northern Asia and Europe; however, due to climate change, new centers of endemicity have arisen.
A. Chmielewska   +13 more
semanticscholar   +1 more source

Chimeric Yellow Fever/Dengue Virus as a Candidate Dengue Vaccine: Quantitation of the Dengue Virus-Specific CD8 T-Cell Response [PDF]

open access: yes, 2000
We have constructed a chimeric yellow fever/dengue (YF/DEN) virus, which expresses the premembrane (prM) and envelope (E) genes from DEN type 2 (DEN-2) virus in a YF virus (YFV-17D) genetic background. Immunization of BALB/c mice with this chimeric virus
Ahmed, Rafi   +3 more
core   +2 more sources

Human case of West Nile neuroinvasive disease in Portugal, summer 2015 [PDF]

open access: yes, 2015
A case of West Nile virus (WNV) infection was reported in the Algarve region, Portugal, in the first week of September 2015. WNV is known to circulate in Portugal, with occasional reports in horses and birds (2004 to 2011) and very sporadically human ...
Alves, M. J.   +7 more
core   +1 more source

Tick-borne encephalitis virus induces chemokine RANTES expression via activation of IRF-3 pathway. [PDF]

open access: yes, 2016
BACKGROUND: Tick-borne encephalitis virus (TBEV) is one of the most important flaviviruses that targets the central nervous system (CNS) and causes encephalitides in humans. Although neuroinflammatory mechanisms may contribute to brain tissue destruction,
Bai, B   +10 more
core   +3 more sources

Non-systemic transmission of tick-borne diseases: a network approach [PDF]

open access: yes, 2016
Tick-Borne diseases can be transmitted via non-systemic (NS) transmission. This occurs when tick gets the infection by co-feeding with infected ticks on the same host resulting in a direct pathogen transmission between the vectors, without infecting the ...
Bajardi, Paolo   +2 more
core   +2 more sources

Pathways for entry of livestock arboviruses into Great Britain : assessing the strength of evidence [PDF]

open access: yes, 2015
The emergence of bluetongue virus and Schmallenberg virus in Great Britain (GB) during the last decade has highlighted the need for understanding the relative importance of the various pathways of the entry of livestock arboviruses so as to help focus ...
Gale, P., Kelly, Louise, Snary, E.L.
core   +1 more source

Predicting wildlife reservoirs and global vulnerability to zoonotic Flaviviruses. [PDF]

open access: yes, 2018
Flaviviruses continue to cause globally relevant epidemics and have emerged or re-emerged in regions that were previously unaffected. Factors determining emergence of flaviviruses and continuing circulation in sylvatic cycles are incompletely understood.
Doyle, Megan M   +5 more
core   +2 more sources

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