The RNA-dependent RNA polymerases (RdRPs) encoded by RNA viruses represent a unique class of nucleic acid polymerases. RdRPs are essential in virus life cycle due to their central role in viral genome replication/transcription processes.
Jieyu Yang +8 more
semanticscholar +1 more source
Extensive diversity of RNA viruses in ticks revealed by metagenomics in northeastern China.
BackgroundTicks act as important vectors of infectious agents, and several emerging tick-borne viruses have recently been identified to be associated with human diseases in northeastern China.
Ziyan Liu +16 more
doaj +1 more source
Efficient assembly and secretion of recombinant subviral particles of the four dengue serotypes using native prM and E proteins. [PDF]
© 2009 Wang et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited ...
Béatrice Nal +10 more
core +8 more sources
The Role of IFITM Proteins in Tick-Borne Encephalitis Virus Infection
TBEV infection may result in encephalitis, chronic illness, or death. TBEV is endemic in northern Asia and Europe; however, due to climate change, new centers of endemicity have arisen.
A. Chmielewska +13 more
semanticscholar +1 more source
Chimeric Yellow Fever/Dengue Virus as a Candidate Dengue Vaccine: Quantitation of the Dengue Virus-Specific CD8 T-Cell Response [PDF]
We have constructed a chimeric yellow fever/dengue (YF/DEN) virus, which expresses the premembrane (prM) and envelope (E) genes from DEN type 2 (DEN-2) virus in a YF virus (YFV-17D) genetic background. Immunization of BALB/c mice with this chimeric virus
Ahmed, Rafi +3 more
core +2 more sources
Human case of West Nile neuroinvasive disease in Portugal, summer 2015 [PDF]
A case of West Nile virus (WNV) infection was reported in the Algarve region, Portugal, in the first week of September 2015. WNV is known to circulate in Portugal, with occasional reports in horses and birds (2004 to 2011) and very sporadically human ...
Alves, M. J. +7 more
core +1 more source
Tick-borne encephalitis virus induces chemokine RANTES expression via activation of IRF-3 pathway. [PDF]
BACKGROUND: Tick-borne encephalitis virus (TBEV) is one of the most important flaviviruses that targets the central nervous system (CNS) and causes encephalitides in humans. Although neuroinflammatory mechanisms may contribute to brain tissue destruction,
Bai, B +10 more
core +3 more sources
Non-systemic transmission of tick-borne diseases: a network approach [PDF]
Tick-Borne diseases can be transmitted via non-systemic (NS) transmission. This occurs when tick gets the infection by co-feeding with infected ticks on the same host resulting in a direct pathogen transmission between the vectors, without infecting the ...
Bajardi, Paolo +2 more
core +2 more sources
Pathways for entry of livestock arboviruses into Great Britain : assessing the strength of evidence [PDF]
The emergence of bluetongue virus and Schmallenberg virus in Great Britain (GB) during the last decade has highlighted the need for understanding the relative importance of the various pathways of the entry of livestock arboviruses so as to help focus ...
Gale, P., Kelly, Louise, Snary, E.L.
core +1 more source
Predicting wildlife reservoirs and global vulnerability to zoonotic Flaviviruses. [PDF]
Flaviviruses continue to cause globally relevant epidemics and have emerged or re-emerged in regions that were previously unaffected. Factors determining emergence of flaviviruses and continuing circulation in sylvatic cycles are incompletely understood.
Doyle, Megan M +5 more
core +2 more sources

