Results 91 to 100 of about 19,991 (204)

Shortest known prion protein allele in highly BSE-susceptible lemurs [PDF]

, 2000
We describe the shortest prion protein allele known to date. Surprisingly, it is found as a polymorphism exactly in a species (prosimian lemurs) which seems highly susceptible to oral infection with BSE-derived prions. The truncation of the prion protein
Gilch, S., Schätzl, H. M., Spielhaupter, C.   +2 more
core   +1 more source

Sheep Feed and Scrapie, France

Emerging Infectious Diseases, 2005
Scrapie is a small ruminant, transmissible spongiform encephalopathy (TSE). Although in the past scrapie has not been considered a zoonosis, the emergence of bovine spongiform encephalopathy, transmissible to humans and experimentally to sheep, indicates
Sandrine Philippe, Christian Ducrot, Pascal Roy, Laurent Remontet, Nathalie Jarrige, Didier Calavas   +5 more
doaj   +1 more source

BSE: Risk, Uncertainty, and Policy Change [PDF]

, 2002
The authors discuss how, in our risk society, a range of potential risks and uncertainties are associated with new technologies and new diseases, such as BSE.
Cummins, Enda, Grace, Pat, McDonnell, Kevin, Ward, Shane   +3 more
core   +1 more source

Seizure Disorders in Goats and Sheep. [PDF]

, 2016
BackgroundGoats and sheep are more likely to be presented for examination for seizures than are cattle, possibly as a consequence of their relatively smaller body size.
Aleman, M, Chigerwe, M
core   +1 more source

Molecular Typing of Protease-Resistant Prion Protein in Transmissible Spongiform Encephalopathies of Small Ruminants, France, 2002–2009

Emerging Infectious Diseases, 2011
The agent that causes bovine spongiform encephalopathy (BSE) may be infecting small ruminants, which could have serious implications for human health. To distinguish BSE from scrapie and to examine the molecular characteristics of the protease-resistant ...
Johann Vulin, Anne-Gaëlle Biacabe, Géraldine Cazeau, Didier Calavas, Thierry Baron   +4 more
doaj   +1 more source

Prion protein-specific antibodies that detect multiple TSE agents with high sensitivity [PDF]

, 2014
This paper describes the generation, characterisation and potential applications of a panel of novel anti-prion protein monoclonal antibodies (mAbs). The mAbs were generated by immunising PRNP null mice, using a variety of regimes, with a truncated form ...
A Gretzschel, A Rhie, A. Richard Alejo Blanco, AB Rodriguez-Martinez, AC Gill, AG Biacabe, AG Biacabe, AG Biacabe, AM Thackray, AM Thackray, Andrew C. Gill, BC Tan, Boon Chin Tan, Byron Caughey, C Farquhar, C Feraudet, C Korth, CA Lee, CA Madampage, CD Orru, Christopher de Wolf, CJ Silva, CM Thuring, CM Thuring, DA Hilton, E Harlow, E Holznagel, E Paramithiotis, E. Fiona Houston, FF Yuan, G Moroncini, G Zanusso, GG Kovacs, H Tveit, HM Geysen, IY Lee, James Alibhai, Jan P. M. Langeveld, JC Manson, JDF Wadsworth, JG Jacobs, JG Jacobs, JP Langeveld, JW Slootstra, K Holada, KL Brown, KM Pan, L Campbell, L Gonzalez, L Gonzalez, L Kirby, L Kirby, L Li, L Pirisinu, L Solforosi, Lauren Campbell, LH Stanker, LJ van Keulen, Lorenzo Gonzalez, M Dawson, M Horiuchi, M Horiuchi, M Jeffrey, M Jeffrey, M Jeffrey, M Jeffrey, M Panigaj, M Polymenidou, M Polymenidou, MF de Marco, MH Groschup, MJ Stack, MM Esiri, N Hunter, N Hunter, N Nakamura, N Privat, Nora Hunter, NV Todd, O Andrievskaia, P Piccardo, PC Klohn, R Rubenstein, RA Barry, RA Williamson, RJ Kascsak, S Halliday, S Harmeyer, S Krasemann, S Lezmi, S McCutcheon, S McCutcheon, Sandra McCutcheon, SL Benestad, SM Whyte, Stuart Martin, T Baron, T Pan, T Seuberlich, T Wisniewski, T Yokoyama, V Beringue, W Goldmann, Y Roettger, Y Shimizu, Y Tang, Y Tang, ZF Kanyo   +107 more
core   +5 more sources

Bovine Spongiform Encephalopathy Infectivity in Greater Kudu (Tragelaphus strepsiceros)

Emerging Infectious Diseases, 2004
Of all the species exposed naturally to the bovine spongiform encephalopathy (BSE) agent, the greater kudu (Tragelaphus strepsiceros), a nondomesticated bovine from Africa, appears to be the most susceptible to the disease.
Andrew A. Cunningham, James K. Kirkwood, Michael Dawson, Yvonne I. Spencer, Robert B. Green, Gerald A.H. Wells   +5 more
doaj   +1 more source

PrPCWD lymphoid cell targets in early and advanced chronic wasting disease of mule deer [PDF]

, 2002
Up to 15% of free-ranging mule deer in northeastern Colorado and southeastern Wyoming, USA, are afflicted with a prion disease, or transmissible spongiform encephalopathy (TSE), known as chronic wasting disease (CWD).
Barillas-Mury, C., Hoover, E.A., Keulen, L.J.M., van, Langeveld, J.P.M., Miller, M.W., Oesch, B., Sigurdson, C.J.   +6 more
core   +2 more sources

Rapid Typing of Transmissible Spongiform Encephalopathy Strains with Differential ELISA

Emerging Infectious Diseases, 2008
The bovine spongiform encephalopathy (BSE) agent has been transmitted to humans, leading to variant Creutzfeldt-Jakob disease. Sheep and goats can be experimentally infected by BSE and have been potentially exposed to natural BSE; however, whether BSE ...
Stéphanie Simon, Jérôme Nugier, Nathalie Morel, Hervé Boutal, Christophe Créminon, Sylvie L. Benestad, Olivier Andréoletti, Frédéric Lantier, Jean-Marc Bilheude, Muriel Feyssaguet, Anne-Gaëlle Biacabe, Thierry Baron, Jacques Grassi   +12 more
doaj   +1 more source

Stochastic Modelling Approach to the Incubation Time of Prionic Diseases

, 2003
Transmissible spongiform encephalopathies like the bovine spongiform encephalopathy (BSE) and the Creutzfeldt-Jakob disease (CJD) in humans are neurodegenerative diseases for which prions are the attributed pathogenic agents.
A. S. Ferreira, A. L. Horwich, B. J. West, D. J. Stekel, G. C. Telling, J. C. Cressoni, J. Collinge, J. D. Murray, J. S. Griffith, M. A. A. da Silva, M. Eigen, R. G. Will, R. M. Anderson, S. B. Prusiner, S. B. Prusiner, S. B. Prusiner   +15 more
core   +1 more source