Results 91 to 100 of about 176,074 (266)

The liver‐brain axis: A multidimensional regulatory network implicated in Alzheimer's disease pathogenesis and clinical implications

Animal Models and Experimental Medicine, EarlyView.
Schematic diagram of the core pathways of the liver‐brain axis in regulating AD. The liver regulates cerebral Aβ deposition, tau phosphorylation, and neuroinflammation through pathways such as metabolic detoxification (urea cycle, ketone body metabolism, glutathione antioxidant system), molecular secretion (APOE, CRP, FGF21, IGF‐1), and Aβ clearance ...
Ning Zhang, Wei Chen, Meng Wang
wiley   +1 more source

Hepatolenticular degeneration-induced hepatic dysfunction with extremely atypical clinical manifestations: a Case Report

Frontiers in Medicine
Hepatolenticular Degeneration (HLD) is a rare condition caused by a genetic copper metabolism disorder and a basal ganglia-dominated degenerative brain disease. Its characteristic clinical features include progressive extrapyramidal symptoms, psychiatric
Zhuang Tao, Jiafeng Zhou, Zhenzhen Jiang, Ya Hu, Shupei Jia, Meixia Wang   +5 more
doaj   +1 more source

Encephalopathy or hepatic encephalopathy?

Journal of Hepatology, 2012
MONTAGNESE, SARA, MERKEL, CARLO, AMODIO, PIERO   +2 more
openaire   +3 more sources

Relationship between blood pressure level with prognosis of acute ischemic stroke patients treated with intravenous thrombolysis: a systematic review and meta-analysis

BMC Neurology
Background Blood pressure (BP) management after intravenous thrombolysis (IVT) for acute ischemic stroke (AIS) remains challenging, and evidence on how BP levels relate to prognosis is inconsistent.
Yingbin Li, Gan Huang, Shaoxue Li, Haolin Liu, Shengju Li, Xiaoxin Bai, Jun Cai   +6 more
doaj   +1 more source

Individualized repetitive intravenous immunoglobulin therapy for a 79-year-old patient with GlyR antibody-positive PERM: a case report and literature review

Frontiers in Immunology
Progressive encephalomyelitis with rigidity and myoclonus (PERM) is a rare, life-threatening variant of stiff-person spectrum disorder that is primarily associated with anti-glycine receptor (GlyR) antibodies.
Xiaojun Liu, Jianwei Zhu, Yuanhong Lei, Xinyuan Yu, Xiujuan Mi   +4 more
doaj   +1 more source

Clinical analysis of Wallenberg's syndrome

Chinese Journal of Contemporary Neurology and Neurosurgery, 2019
Objective To summarize the clinical features of Wallenberg syndrome (WS). Methods Clinical manifestations, imaging features, etiology and predisposing factors, treatment and prognosis of 36 WS patients from March 2015 to October 2017 were retrospectively
Jie HU, Rui-qing XU, Xiang-long LÜ, Yun-qin WANG, Ying GAO   +4 more
doaj  

Linking physical stimulation to molecular responses: The role and value of exosomes in mediating the systemic effects of Chinese Tuina

Clinical and Translational Discovery
Chinese Tuina, a fundamental manual therapy technique in traditional Chinese medicine (TCM), treats diseases by applying precisely regulated mechanical forces to the human body.
Lifen Zhan, Ji Zhang, Yiping Chen, Suyu Chen, Xiantao Tai   +4 more
doaj   +1 more source

From Interferon Signature to the Clinical Landscape: Type I Interferonopathies

Arthritis &Rheumatology, EarlyView.
Objective TypeI interferonopathies are heterogeneous diseases driven by dysregulated type I interferon (IFN‐I) signaling. Diagnosis is challenging due to clinical/molecular variability and the need for IFN‐I quantification. The aim of this study was to characterize the clinical, immunologic, genetic, molecular profiles of patients with suspected ...
Ismail Yaz, Seza Ozen, Hacer Neslihan Bildik, Canberk Ipsir, Dilara Unal, Saliha Esenboga, Begum Cicek, Mehmet Emin Seker, Fatima Aerts‐Kaya, Seher Sener, Mehmet Orhan Erkan, Hanife Avci, Deniz Cagdas, Ilhan Tezcan   +13 more
wiley   +1 more source

Charlotte Pommer: Resistance fighter and female pioneer of German anatomy

Anatomical Sciences Education, EarlyView.
Abstract This article examines the biography and unique case of Charlotte Pommer (1914–2004), the only anatomist documented to have left the field during the Nazi period after encountering the regime's victims on the dissection table. While she is known for her resistance activities, newly presented documentation reveals her role as the provisional ...
Tim S. Goldmann
wiley   +1 more source

Association between cumulative atherogenic index of plasma and dementia risk score in middle-aged and elderly adults: a longitudinal analysis of the CHARLS cohort

European Journal of Medical Research
Background Dementia has become an important public health challenge as the aging population in China accelerates, highlighting the need to identify modifiable risk factors.
Tongjie Zhang, Qian Xu, Jie Zhou
doaj   +1 more source