Results 181 to 190 of about 176,074 (266)

Comparative multicenter evaluation of thalamic neuromodulation for treatment‐resistant epilepsy in children

open access: yesEpilepsia, EarlyView.
Abstract Objective Use of neuromodulation strategies targeting thalamic nuclei, including deep brain stimulation (DBS) and responsive neurostimulation (RNS), for treatment of pediatric drug‐resistant epilepsy (DRE) is increasing, despite limited evidence for efficacy and safety. We present the initial results from the Comparative Multicenter Evaluation
Samuel A. Tenhoeve   +28 more
wiley   +1 more source

Refining diagnostic boundaries and electroclinical profiles of Lennox–Gastaut syndrome through unsupervised clustering

open access: yesEpilepsia, EarlyView.
Abstract Objective Lennox–Gastaut syndrome (LGS) is a developmental and epileptic encephalopathy defined by polymorphic seizures, intellectual disability (ID), and characteristic electroencephalographic (EEG) patterns. The applicability and biological validity of current electroclinical criteria remain debated.
Emanuele Cerulli Irelli   +12 more
wiley   +1 more source

Emergency treatment delay and underdosing are associated with poor outcome in non‐convulsive status epilepticus

open access: yesEpilepsia, EarlyView.
Abstract Nonconvulsive status epilepticus (NCSE) is difficult to recognize in the emergency department (ED), where onset is often unknown and treatment may be delayed. To what extent treatment timing and dose adequacy are associated with outcome in NCSE remains debated.
Francesco Misirocchi   +6 more
wiley   +1 more source

Perils and progress in epilepsy surgery utilization: Twenty‐five years later

open access: yesEpilepsia, EarlyView.
Abstract More than 25 years have passed since the first randomized controlled trial (RCT) established that surgery is superior to continued anti‐seizure medication (ASM) for drug‐resistant temporal lobe epilepsy, and nearly as long since a joint practice parameter urged that appropriate surgical candidates be referred to a specialized center for ...
Dario J. Englot
wiley   +1 more source

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