Results 211 to 220 of about 414,897 (392)

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons   +17 more
wiley   +1 more source

Practical management of repeated life‐threatening status epilepticus in Alternating Hemiplegia of Childhood: Case report and literature review

open access: yesEpileptic Disorders, EarlyView.
Abstract Background Alternating Hemiplegia of Childhood (AHC) is a severe channelopathy that manifests before 18 months of age, primarily caused by pathogenic variants in the ATP1A3 gene. It is characterized by recurrent and disabling episodes of plegia, dystonia, dysautonomia, along with chronic neurological features and cardiac arrhythmias. About 50%
Ramona Cordani   +8 more
wiley   +1 more source

Lymphostatic encephalopathy and vitamins [PDF]

open access: bronze, 1973
Ethel Földi-Börcsök, M. Földi
openalex   +1 more source

Seminars in epileptology: How to diagnose status epilepticus in adults and children

open access: yesEpileptic Disorders, EarlyView.
Abstract Status epilepticus (SE) can be regarded as the most severe expression of seizure activity characterized by a low probability of spontaneous cessation and mechanisms leading to metabolic and inflammatory derangements with increased risk of brain damage, alterations of neural networks, and potentially life‐threatening systemic complications ...
M. Leitinger   +12 more
wiley   +1 more source

BILIRUBIN ENCEPHALOPATHY IN THE GUNN RAT

open access: bronze, 1967
Henry S. Schutta, Lois Johnson
openalex   +1 more source

Reduction of interictal epileptic burden by pulsatile corticoid therapy in children with drug‐resistant epilepsy—How stable is the effect?

open access: yesEpileptic Disorders, EarlyView.
Abstract Objective The systematic use of pulsatile corticosteroid therapy (PCT) in children with drug‐resistant epilepsy has been shown to reduce epileptic activity. However, it remains unclear how long this effect will last. The objective of this study was therefore to evaluate the stability of the effect of PCT by assessing the interictal epileptic ...
Katharina Schiller   +9 more
wiley   +1 more source

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