Results 91 to 100 of about 2,462,637 (289)
IEEE AccessThe study of genre preferences of different doctors by leveraging their handled computed tomography (CT) images from multiple hospital databases offers a compelling field of AI-based medical treatment, especially in terms of deciphering and categorizing ...
Haoyu Chen, Jun Li
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Subquadratic time encodable codes beating the Gilbert-Varshamov bound
, 2018 We construct explicit algebraic geometry codes built from the Garcia-Stichtenoth function field tower beating the Gilbert-Varshamov bound for alphabet sizes at least 192. Messages are identied with functions in certain Riemann-Roch spaces associated with
Narayanan, Anand Kumar, Weidner, Matthew
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pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Mathematical and Computational ApplicationsThe Latent Space Perspicacity and Interpretation Enhancement (LS-PIE) framework enhances dimensionality reduction methods for linear latent variable models (LVMs).
Jesse Stevens +2 more
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On the Problem of Optimal Path Encoding for Software-Defined Networks
, 2016 Packet networks need to maintain state in the form of forwarding tables at each switch. The cost of this state increases as networks support ever more sophisticated per-flow routing, traffic engineering, and service chaining.
Hari, Adiseshu +2 more
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Frontiers in Aging Neuroscience, 2015 Memory capacity suffers an age-related decline, which is supposed to be due to a generalized slowing of processing speed and to a reduced availability of processing resources.
Diego ePinal +2 more
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Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
A dynamic neural resource model bridges sensory and working memory
eLifeProbing memory of a complex visual image within a few hundred milliseconds after its disappearance reveals significantly greater fidelity of recall than if the probe is delayed by as little as a second.
Ivan Tomić, Paul M Bays
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