Results 131 to 140 of about 3,692,662 (365)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

A Hybrid Quantum Encoding Algorithm of Vector Quantization for Image Compression

open access: yes, 2006
Many classical encoding algorithms of Vector Quantization (VQ) of image compression that can obtain global optimal solution have computational complexity O(N).
Grover L K   +11 more
core   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Hippocampal-prefrontal input supports spatial encoding in working memory

open access: yesNature, 2015
Spatial working memory, the caching of behaviourally relevant spatial cues on a timescale of seconds, is a fundamental constituent of cognition. Although the prefrontal cortex and hippocampus are known to contribute jointly to successful spatial working ...
T. Spellman   +5 more
semanticscholar   +1 more source

The IQ‐compete assay for measuring mitochondrial protein import efficiencies in living yeast cells

open access: yesFEBS Letters, EarlyView.
The efficiency of mitochondrial protein import depends on the properties of the newly synthesized precursor proteins. The Import and de‐Quenching Competition (IQ‐compete) assay is a novel method to monitor the import efficiency of different proteins by fluorescence in living yeast cells.
Yasmin Hoffman   +3 more
wiley   +1 more source

The Role of Short-term Consolidation in Memory Persistence

open access: yesAIMS Neuroscience, 2015
Short-term memory, often described as working memory, is one of the most fundamental information processing systems of the human brain. Short-term memory function is necessary for language, spatial navigation, problem solving, and many other daily ...
Timothy J. Ricker
doaj   +1 more source

Pre-Congestion Notification Encoding Comparison [PDF]

open access: yes, 2007
DiffServ mechanisms have been developed to support Quality of Service (QoS). However, the level of assurance that can be provided with DiffServ without substantial over-provisioning is limited.
Chan, K., Karagiannis, G.
core   +2 more sources

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

open access: yesFEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello   +6 more
wiley   +1 more source

Time Series Forecasting via Derivative Spike Encoding and Bespoke Loss Functions for Spiking Neural Networks

open access: yesComputers
The potential of neuromorphic (NM) solutions often lies in their low-SWaP (Size, Weight, and Power) capabilities, which often drive their application to domains that could benefit from this.
Davide Liberato Manna   +4 more
doaj   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

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