Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
Commentary: Stimulation of the Posterior Cingulate Cortex Impairs Episodic Memory Encoding
Marie-Lucie Read, Rikki Lissaman
doaj +1 more source
Beyond Context-Transfer Effects: Attenuated Familiarity During Virtual Reality-Based Retrieval Across Different Encoding Modalities. [PDF]
Kisker J +3 more
europepmc +1 more source
Glymphatic Dysfunction Reflects Post‐Concussion Symptoms: Changes Within 1 Month and After 3 Months
ABSTRACT Objective Mild traumatic brain injury (mTBI) may alter glymphatic function; however, its progression and variability remain obscure. This study examined glymphatic function following mTBI within 1 month and after 3 months post‐injury to determine whether variations in glymphatic function are associated with post‐traumatic symptom severity ...
Eunkyung Kim +3 more
wiley +1 more source
Affect Labeling During Pictorial Encoding Enhances Their Recognition and Reduces Amygdalar Responses to Negative Pictures. [PDF]
Lin H, Jin X, Jin H.
europepmc +1 more source
Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron +5 more
wiley +1 more source
Encoding neural representations of time-continuous stimulus-response transformations in the human brain with advanced deep neural networks. [PDF]
Haberland S, Ruge H, Frimmel H.
europepmc +1 more source
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Atomic-scale physical unclonable functions in solids. [PDF]
Chai Z +9 more
europepmc +1 more source

