Results 151 to 160 of about 230,478 (367)
Germline variants in CDKN2A wild‐type melanoma prone families
Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen+5 more
wiley +1 more source
Encrypted Qubits can be Cloned [PDF]
We show that encrypted cloning of unknown quantum states is possible. Any number of encrypted clones of a qubit can be created through a unitary transformation, and each of the encrypted clones can be decrypted through a unitary transformation. The decryption of an encrypted clone consumes the decryption key, i.e., only one decryption is possible, in ...
arxiv
Advanced Encryption Standard (AES) - An Update [Invited Paper] [PDF]
Lars R. Knudsen
openalex +1 more source
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu+11 more
wiley +1 more source
Identity-Based Encryption from the Weil Pairing
D. Boneh, M. Franklin
semanticscholar +1 more source
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau+11 more
wiley +1 more source
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit+19 more
wiley +1 more source
Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson+11 more
wiley +1 more source
Intermittent Encryption Strategies for Anti-Eavesdropping Estimation [PDF]
In this paper, an anti-eavesdropping estimation problem is investigated. A linear encryption scheme is utilized, which first linearly transforms innovation via an encryption matrix and then encrypts some components of the transformed innovation. To reduce the computation and energy resources consumed by the linear encryption scheme, both stochastic and
arxiv
Fuzzy Identity-Based Encryption
A. Sahai, Brent Waters
semanticscholar +1 more source