Results 151 to 160 of about 441,462 (365)
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
A Proposal for a New Block Encryption Standard
, 1991 Xuejia Lai, James L. Massey
openalex +1 more source
Public Key Encryption with Keyword Search
International Conference on the Theory and Application of Cryptographic Techniques, 2004 D. Boneh +3 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
An Elgamal Encryption Scheme of Fibonacci Q-Matrix and Finite State Machine
Journal of Applied Computer Science & Mathematics, 2015 Cryptography is the science of writing messages in unknown form using mathematical models. In Cryptography, several ciphers were introduced for the encryption schemes.
B. Ravi Kumar +2 more
doaj
Low-Complexity Versatile Finite Field Multiplier in Normal Basis
EURASIP Journal on Advances in Signal Processing, 2002 A low-complexity VLSI array of versatile multiplier in normal basis over is presented. The finite field parameters can be changed according to the user′s requirement and make the multiplier reusable in different applications.
Zhang Chang Nian, Li Hua
doaj +1 more source
New Attacks on PKCS#1 v1.5 Encryption [PDF]
, 2000 Jean-Sébastien Coron +3 more
openalex +1 more source
Molecular Oncology, EarlyView.In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková +14 more
wiley +1 more source