Results 141 to 150 of about 253,555 (314)
Exploring the mechanism of saffron in treating viral myocarditis using network pharmacology and molecular docking. [PDF]
Zhu Z, Hu J, Li L.
europepmc +1 more source
ZDHHC17 palmitoylates CDK4, which together with TRAF6‐mediated ubiquitination, drives cell cycle progression and immune surveillance, revealing a rational combination of CDK4 inhibitors with immune checkpoint blockers for ZDHHC17‐driven cancers. ABSTRACT Uncontrolled cell cycle progression is a hallmark of cancer, tightly regulated by both intrinsic ...
Zekang Wang +7 more
wiley +1 more source
Metagenomic profiling of biliary microbiota reveals distinct microbial and functional features in cholelithiasis and cholecystic polyps. [PDF]
Yu Y, Wang C, Pan X, Ding C, Chen J.
europepmc +1 more source
Encyclopedia of Bioethics Volume 2
The Encyclopedia of Bioethics is the first encyclopedia in its field. Its purpose is to synthesize, analyze, and compare the positions taken on the problems of bioethics, in the past as well as in the present, to indicate which issues require further ...
core
Ferritinophagy Rewires Carnitine‐Dependent Lipid Metabolism to Inhibit PRRSV and IAV Replication
NCOA4‐mediated ferritinophagy reprograms carnitine metabolism by disrupting Fe‐S cluster biogenesis, thereby establishing an iron‐lipid axis that suppresses various viruses, including PRRSV and IAV. However, viruses counteract this mechanism by degrading NCOA4.
Kaifeng Guan +7 more
wiley +1 more source
Identification of potential hub genes and drugs in septic liver injury: A bioinformatic analysis. [PDF]
Yang Y +5 more
europepmc +1 more source
This study presents a ″trash‐to‐treasure″ strategy that converts harmful joint overloads into beneficial electrical cues. The biodegradable MagPie, by providing piezoelectrical stimulation and releasing Mg2+ during mastication, exerts synergistic pro‐regenerative and anti‐inflammatory effects on Prg4+ cells via the ECM‐mediated FAK‐PI3K‐Akt axis ...
Shi‐Yang Feng +10 more
wiley +1 more source

