Results 151 to 160 of about 253,555 (314)

Identification of RUNX1 as a Biomarker for Right Ventricular Remodeling in Pulmonary Arterial Hypertension Using WGCNA. [PDF]

Pulm Circ
Chen W, Peng M, Chen Y, Luo J, Chen J, Qiu H, Li J.   +6 more
europepmc   +1 more source

Targeting PLD3 Reverses the Immunosuppressive Niche by Reprogramming Tumor‐Associated Macrophages and Potentiates Antitumor Immunity

Advanced Science, EarlyView.
PLD3 activates the lysosomal‐AKT‐NF‐κB axis to drive cellular senescence in macrophages, establishing an immunosuppressive TME by limiting the infiltration of cytotoxic T, NK, and NKT cells, which confers resistance to anti‐PD‐1 therapy. Abrine inhibits PLD3 expression, restoring antitumor immunity and synergizing with anti‐PD‐1 treatment.
Xingtu Qin, Qiong Li, Xuemei Xu, Yuhan Wu, Yin Zhu, Jieqiong Wu, Yuan Fang, Qiubei Chen, Shuyang Wang, Jiang Yu, Yaping Ye, Hongli Jiao   +11 more
wiley   +1 more source

Metaphorical perceptions of secondary school students regarding the concept of generative artificial intelligence. [PDF]

Eur J Pediatr
Özbay Ö.
europepmc   +1 more source

The new encyclopedia britannica vol : 2 bayen-ceanothus. micropaedia.

, 2014
Encyclopedia ENCYCLOPEDIA
core  

Targeting ANGPTL3 and IL‐33/ST2 Ameliorates Diabetic Kidney Disease by Reducing Lipotoxicity, Alleviating Inflammation and Inhibiting Fibrosis

Advanced Science, EarlyView.
Dual targeting of ANGPTL3 and IL‐33/ST2 attenuates diabetic kidney disease by reprogramming lipid–inflammatory crosstalk. This strategy reduces renal lipotoxicity, suppresses inflammatory activation, and limits fibrotic remodeling, thereby preserving kidney structure and function and highlighting a mechanism‐guided therapeutic approach for metabolic ...
Zhuojin Li, Zhonglian Cao, Rongrui Zhou, Xu Cheng, Xiaozhi Hu, Shuwen Xu, Zihan Dou, Ling Du, Dianwen Ju   +8 more
wiley   +1 more source

THE molecular mechanisms underlying synovial fibroblast differentiation in knee osteoarthritis revealed by single-cell transcriptome sequencing. [PDF]

Medicine (Baltimore)
Chen H, Fei J, Zhang K.
europepmc   +1 more source

The new encyclopedia britanica volume 1 : micropaedia 15th edition a-a

, 2014
Encyclopedia ENCYCLOPEDIA
core  

NFYB Integrates Hormonal Signals into Tissue Allometry by Promoting Protein Biosynthesis

Advanced Science, EarlyView.
In the American cockroach, NFYB acts as a spatiotemporin that translates distinct hormonal cues into tissue‐specific allometry. Juvenile hormone activates NFYB in the early fat body, while 20‐hydroxyecdysone induces it in late wing pads. NFYB then promotes protein biosynthesis via core translational machinery, driving differential growth across the ...
Fangfang Liu, Shiming Zhu, Sishi Xia, Xiaoshuai Zhang, Qin Li, Zhanquan Zeng, Yuqing Liu, Wanyin Liang, Guanyu Zhou, Erxia Du, Suning Liu, Sheng Li   +11 more
wiley   +1 more source

Network pharmacology and Mendelian randomization analysis to unravel the mechanism of Qingwen Baidu Decoction in sepsis treatment. [PDF]

Medicine (Baltimore)
Wang W, Ruan Y, Wu X, Li L, Liu N, Li Y.
europepmc   +1 more source

Britannica Concise Encyclopedia

, 2006
The Encyclopedia Britannica
core