Results 181 to 190 of about 1,225,935 (368)

A Dual Approach with Organoid and CRISPR Screening Reveals ERCC6 as a Determinant of Cisplatin Resistance in Osteosarcoma

Advanced Science, EarlyView.
This study utilizes patient‐derived osteosarcoma organoids and CRISPR screening to identify ERCC6 and HNRNPM as key mediators of cisplatin resistance via the PI3K/AKT pathway and BAX alternative splicing. These findings provide novel insights and potential therapeutic targets for overcoming chemoresistance in osteosarcoma.
Ruiling Xu, Sai Zhu, Wenchao Zhang, Haodong Xu, Chao Tu, Honghui Wang, Lu Wang, Na He, Tang Liu, Xiaoning Guo, Xiaolei Ren, Zhihong Li   +11 more
wiley   +1 more source

Molecular targets of vortioxetine mediating glioblastoma suppression revealed by gene and protein network analyses and molecular docking simulations. [PDF]

Int J Neuropsychopharmacol
Zhuo C, Li C, Zhang Q, Yang L, Zhang Y, Chen X, Ma X, Li R, Wang L, Tian H.   +9 more
europepmc   +1 more source

ENCYCLOPEDIA OF CHILD GUIDANCE

, 1947
Winn Ralph B
openalex   +1 more source

Handbuch Der Insektizidkunde (Encyclopedia of Insecticides) [PDF]

, 1967
S. A. Hall
openalex   +1 more source

Value [Encyclopedia Entry] [PDF]

, 2005
Davis, John B.
core   +1 more source

Gut Metabolite Indole‐3‐Propionic Acid Regulates Macrophage Autophagy Through PPT1 Inhibiting Aging‐Related Myocardial Fibrosis

Advanced Science, EarlyView.
IPA is an intestinal tryptophan metabolite whose effects decline with decreased heart function. Supplementing IPA can alleviate the aging‐related myocardial fibrosis through PPT1. PPT1 is a key protein localized to lysosomes, and IPA can restore macrophage autophagy function by regulating PPT1 expresssions, thereby reducing aging‐related myocardial ...
Jing Lu, Hongyan Wang, Haiyu Zhang, Jiahao Li, Hanqi Li, Qiuyu Chen, Dongyu Han, Jialiang Liu, Lin Lv, Jie Xiong, Keying Yuan, Xianpeng Wei, Siqi Sheng, Fukai Liu, Yuanqi Shi, Zengxiang Dong, Yue Li   +16 more
wiley   +1 more source

Single cell sequencing and computational findings reveal anti-estrogen receptor-positive breast cancer roles of formononetin. [PDF]

Sci Rep
Li B, Li S, Li R, Li M, Huang Z.
europepmc   +1 more source

Family (Encyclopedia entry) [PDF]

, 2008
Coles, Roberta L.
core   +1 more source

Weight Cycling Deregulates Eating Behavior in Mice via the Induction of Durable Gut Dysbiosis

Advanced Science, EarlyView.
Weight cycling in Humans is suspected to dysregulate eating behavior. Mice submitted to body weight cycling by alternating western‐type and regular chow diets display increased hedonic appetite when exposed to a palatable diet, reminiscent of binge‐eating episodes.
Mélanie Fouesnard, Adélie Salin, Sandy Ribes, Magali Monnoye, Gaëlle Champeil‐Potokar, Marie‐Sabelle Hjeij, Gwénaëlle Randuineau, Léa Le Gleau, Selma Ben Fradj, Catherine Philippe, Alexandre Benani, Isabelle Denis, Véronique Douard, Gaëlle Boudry   +13 more
wiley   +1 more source

Exploration of Liuwei Dihuang Pill on periodontitis based on network pharmacology and molecular docking. [PDF]

Medicine (Baltimore)
Luo Y, Liu C, Liu J, Wang H, Fu Y, Liu Y.   +5 more
europepmc   +1 more source