Results 201 to 210 of about 1,264,841 (338)

An encyclopedia of Keynesian economics

open access: gold, 1997
Thomas Cate   +2 more
openalex   +2 more sources

Efferocytosis‐Driven Polyamine Metabolism in Macrophages Enhances Cancer Stem Cell Enrichment after Chemotherapy in Ovarian Cancer

open access: yesAdvanced Science, EarlyView.
Chemotherapy‐induced efferocytosis drives ovarian cancer stem cell enrichment. By engulfing apoptotic cancer cells, macrophages upregulate ODC1 and produce putrescine, which elevates osteopontin (OPN) expression. Secreted OPN then activates the CD44 receptor on cancer cells, promoting stemness and chemoresistance.
Wenhan Li   +19 more
wiley   +1 more source

Intertidal Warfare: Synergistic Allelopathy Mediates Spatial Competition between Two Marine Calcareous‐Shelled Sessile Organisms

open access: yesAdvanced Science, EarlyView.
This study reveals a hidden chemical weapon among calcareous‐shelled sessile organisms in the intertidal zone: the barnacle Balanus albicostatus releases a synergistic blend of palmitic acid and 1‐palmitoyl‐sn‐glycero‐3‐phosphocholine as the allelochemical with the inhibitory activity against attachment of the mussel Vignadula atrata, which may mediate
Zhuo Li   +9 more
wiley   +1 more source

Hepatocyte Mettl3 Deficiency Drives Primary Sclerosing Cholangitis and Liver Fibrosis via Cholangiocyte‐Macrophage Crosstalk

open access: yesAdvanced Science, EarlyView.
Schematic illustration demonstrating that hepatic Mettl3 depletion significantly elevates the secretion of Mif and Csf1. This elevation facilitates Trem2+ macrophage infiltration and triggers cholangiocyte remodeling through the Spp1‐Cd44 interaction, resulting in spontaneous PSC development in vivo.
Wenting Pan   +19 more
wiley   +1 more source

Tear proteomics reveals biomarkers for visual field progression in normal-tension glaucoma. [PDF]

open access: yesInt J Ophthalmol
Tang LW   +7 more
europepmc   +1 more source

CLinNET: An Interpretable and Uncertainty‐Aware Deep Learning Framework for Multi‐Modal Clinical Genomics

open access: yesAdvanced Science, EarlyView.
Identifying disease‐causing genes in neurocognitive disorders remains challenging due to variants of uncertain significance. CLinNET employs dual‐branch neural networks integrating Reactome pathways and Gene Ontology terms to provide pathway‐level interpretability of genomic alterations.
Ivan Bakhshayeshi   +5 more
wiley   +1 more source

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