Results 111 to 120 of about 41,326 (302)
Self‐Assembling Hybrid Hydrogel Reprograms the Stromal Vascular Fraction to Treat Osteoarthritis
Advanced Science, EarlyView.This study presents a bioinspired injectable hydrogel that enhances the therapeutic potential of stem cell‐rich stromal vascular fraction for treating osteoarthritis. By reprogramming cell behavior through epigenetic modulation, the hydrogel promotes cartilage regeneration and reduces joint damage in a rat model, offering a promising new approach for ...
Waifang Hou +23 more
wiley +1 more source
Advanced Science, EarlyView.This study developed a hierarchical targeting nanoplatform, siTREM2@ETP‐PEOz‐OMVs, against triple‐negative breast cancer (TNBC) bone metastasis. It precisely delivers therapeutic siTREM2 to monocytes/macrophages within the metastatic niche. This intervention dually regulates cell fate: reprogramming immunosuppressive macrophages and inhibiting ...
Fanglu Chen +12 more
wiley +1 more source
Revisiting materials for teaching languages for specific purposes [PDF]
, 2011 Teaching materials in languages for specific purposes have evolved in the last few years dramatically. The Internet currently plays a significant role in such development and has permitted both a wider range of resources and its free availability almost ...
Jesús García Laborda,
core
Advanced Science, EarlyView.ABSTRACT Our previous clinical trials had demonstrated that neoadjuvant hypofractionated radiotherapy (HFRT) combined with immunotherapy yields promising clinical outcomes in locally advanced rectal cancer (LARC). However, this combined modality benefits only a subset of patients, highlighting the need to uncover the mechanisms underlying how ...
Lichao Liu +12 more
wiley +1 more source
Ukrainian Electronic Encyclopedias
Studia Lexicographica, 2018 This article describes contemporary Ukrainian electronic encyclopedias, proposes their general review and characterizes their main types and the thematic and typological peculiarities of both online encyclopedic products and electronic versions of ...
Yaroslav Pylynskyi
doaj
, 2014 Since the inception of printing in Europe in the fifteenth century, encyclopedias have become popular and widespread all over the continent. During the eighteenth century, dictionaries and other knowledge-communicating books constituted a major part of the book market, thereby defining everyday knowledge, including information about the entire world ...
openaire +1 more source
Advanced Science, EarlyView.4‐HBA upregulates NKIRAS2 levels, inhibiting the activation of the NF‐κB pathway and subsequently reducing the levels of neuroinflammatory markers. This modulation helps restore normal mood and behavior in hyperlipidemic conditions, providing a potential therapeutic strategy for managing hyperlipidemia‐associated depression.
Ying Zhang +7 more
wiley +1 more source
Computers, the internet, and cheating among secondary school students: Some implications for educators [PDF]
, 2004 This article investigates in greater depth one particular aspect of cheating within secondary education and some implications for measuring academic achievement.
Conradson, Stacey +1 more
core +1 more source
Advanced Science, EarlyView.TRF enriches Ruminococcus, a bacterial genus producing SCFAs, and activates the epithelial HIF‐1α signaling pathway. This mechanism protects the colonic mucosa from inflammatory insults in colitis models. Mechanistically, gut lactate production during starvation and refeeding mediates H4K12la, which increases SLC9A3 expression and creates an acidic gut
Linwen Huang +17 more
wiley +1 more source