Results 51 to 60 of about 78,649 (333)

On the modeling of a national encyclopedic-and-educational service

open access: yesЕнциклопедичний Вісник України, 2019
The article defends the necessity to establish a national help service titled Navchannia Navprostets (Learn Direct). It would be a not-for-profit telephone line based on modern encyclopedias of Ukraine.
Serhii Boltivets
doaj   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Academic online encyclopedias in view of the recent information space developing

open access: yesЕнциклопедичний Вісник України, 2018
The article describes the phenomenon of the electronic encyclopedia activity and investigates the electronic Internet encyclopedias created by the institutions of the National Academy of Sciences of Ukraine.
Mykola Zhelezniak, Oleksandr Ishchenko
doaj   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

open access: yesFEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

The coronavirus disease COVID-19’s coverage in Ukrainian and European encyclopedias

open access: yesЕнциклопедичний Вісник України, 2020
Today, humans have the phase of the social organization evolution, in which information, communication technologies, and knowledge are fundamental objects of production, as well as the digital environment is an important space for the development of ...
Mykola Zhelezniak, Oleksandr Ishchenko
doaj   +1 more source

Amazing Space: Stellar Spire in the Eagle Nebula Lithograph [PDF]

open access: yes, 2005
This lithograph features Hubble Space Telescope images and includes text that describes and explains the images. There is also an accompanying inquiry-based classroom activity entitled “In Search of Star Formation.” This activity is designed to encourage
Bonnie Eisenhamer
core  

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

open access: yesFEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli   +9 more
wiley   +1 more source

A utilização de enciclopédias em bibliotecas públicas e escolares da Região Metropolitana de Belo Horizonte: relato de pesquisa

open access: yesCiência da Informação, 1993
Analisa a utilização de enciclopédias gerais em bibliotecas públicas e escolares, mediante entrevista com profissionais de informação atuantes do setor de referência de 31 bibliotecas públicas e escolares da Região Metropolitana de Belo Horizonte ...
Bernadete Santos Campello   +2 more
doaj  

Encyclopedia publishing as a technology for promoting and propagation of human state values

open access: yesЕнциклопедичний Вісник України, 2017
Encyclopedias are studied in view of an effect of the encyclopedic information on the public opinion. It is noted that during the Soviet era, the most important encyclopedias, such as the Soviet Encyclopedia or the Ukrainian Soviet Encyclopedia ...
Ruslan Pylypchuk
doaj   +1 more source

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