Results 61 to 70 of about 41,046 (283)

A 3D Astrocyte Microenvironment Model Enables Rapid Ca2+‐Resolved Analysis and Therapeutic Modulation of Oxidative Neuroinflammation

open access: yesAdvanced Healthcare Materials, EarlyView.
This work presents ARC‐3D, a soft 3D model that recreates how brain support cells, called astrocytes, react to oxidative stress. The system visualizes rapid calcium changes and inflammatory signals, and shows how the drug KDS12025 can protect cells from damage. ARC‐3D offers a simple, reliable way to study early drivers of brain inflammation.
Ju‐Kang Kim   +6 more
wiley   +1 more source

Knowledge supply chains in an age of truth decay: The role of encyclopedias

open access: yesStudia Lexicographica, 2023
Our information sphere—the space where we not only express our opinions, but where we also form our opinions—is facing significant challenges. The core trends of »truth decay«— growing disagreement about facts; blurred lines between opinion and fact ...
Naja Bentzen
doaj  

Ukrainian online encyclopedias: development trends and place in the information space of our state

open access: yesЕнциклопедичний Вісник України, 2017
The analysis of online encyclopedias in the Ukrainian information space is done in this paper. It is investigated that online encyclopedias are divided into two large groups: digital analogues of printed editions, for example the online Encyclopedia of ...
Mykola Zhelezniak
doaj   +1 more source

Amazing Space: Stellar Spire in the Eagle Nebula Lithograph [PDF]

open access: yes, 2005
This lithograph features Hubble Space Telescope images and includes text that describes and explains the images. There is also an accompanying inquiry-based classroom activity entitled “In Search of Star Formation.” This activity is designed to encourage
Bonnie Eisenhamer
core  

Geometrical simplification of the dipole-dipole interaction formula

open access: yes, 2009
Many students meet quite early this dipole-dipole potential energy when they are taught electrostatics or magnetostatics, and it is also a very popular formula, featured in the encyclopedias.
Kocbach, Ladislav, Lubbad, Suhail
core   +1 more source

Macrophage Membrane‐Cloaked, ROS‐Triggered Quercetin Nanocarriers Target Ovarian Lesions to Treat Polycystic Ovary Syndrome

open access: yesAdvanced Healthcare Materials, EarlyView.
The synthesis process of MM@PCD@QNPs and its potential mechanism for treating PCOS. (A) Assembly steps of MM@PCD@QNPs. (B) Synthesis and decomposition of MM@PCD@QNPs. (C) Potential therapeutic mechanisms of MM@PCD@QNPs for PCOS. PCD, PABP conjugated with DEX polymer; QUR, quercetin; CDI, N, N′‐carbonyldiimidazole; DEX, dextran; PABP, 4‐(hydroxymethyl ...
Wenzhu Li   +9 more
wiley   +1 more source

Zinc‐Containing Bioactive Glass Programs Macrophage Polarization through Extracellular Traps Regulation for Enhanced Diabetic Wound Healing

open access: yesAdvanced Healthcare Materials, EarlyView.
Zinc‐containing bioactive glass (ZnBG) promotes diabetic wound healing by regulating macrophage extracellular traps (METs). Specifically, ZnBG reduces oxidative stress and inhibits the PAD4 and NLRP3/caspase‐1/GSDMD signaling pathways, thereby suppressing MET formation.
RuiYang Sun   +11 more
wiley   +1 more source

Information and Experience in Metaphor: A Perspective From Computer Analysis [PDF]

open access: yes, 1986
Novel linguistic metaphor can be seen as the assignment of attributes to a topic through a vehicle belonging to another domain. The experience evoked by the vehicle is a significant aspect of the meaning of the metaphor, especially for abstract metaphor,
Russell, Sylvia Weber
core   +2 more sources

Ultrasound‐Responsive Dual‐Prodrug Nanoassembly for “Fenestrae‐Restoration Strategy” in Liver Fibrosis Therapy

open access: yesAdvanced Materials, EarlyView.
ABSTRACT Liver fibrosis is a serious yet reversible intermediate stage in the progression of liver disease, which can ultimately advance to cirrhosis and hepatocellular carcinoma. Targeted and selective inhibition of activated hepatic stellate cells (aHSCs) has emerged as a promising therapeutic strategy for the treatment of liver fibrosis.
Shutong Liu   +8 more
wiley   +1 more source

Immune and Stem Cell‐Mediated Bactericidal Amplification and Bone Remodeling for Infection Clearance and Osteointegration

open access: yesAdvanced Materials, EarlyView.
A pH‐responsive biomaterial interface integrates bactericidal peptides, cell‐recruiting peptides, and magnesium ions into a multifunctional system. Infection‐induced acidification triggers antimicrobial peptide release while cell‐recruiting peptides mobilize bone marrow stem cells.
Zhenyu Li   +9 more
wiley   +1 more source

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