Results 141 to 150 of about 175,061,202 (302)
Care without walls: Generalist-led integrated home health for life’s final chapter
Annals, Academy of Medicine, SingaporeWei Chyi Rae-Ann Tan +5 more
doaj +1 more source
End-of-life care in paediatrics [PDF]
British Journal of Nursing, 2020 Rosengarten, Leah, Carr, Elizabeth
openaire +2 more sources
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank
FEBS Open Bio, EarlyView.Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer +7 more
wiley +1 more source
Threonine 348 regulates the subcellular localization of PTEN
FEBS Open Bio, EarlyView.Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley +1 more source
Valuing qalys at the end of life [PDF]
There have been changes in the way that NICE evaluates medical treatments for patients who are in the last stages of their lives. If medicines fulfil some criteria to be considered “end of life” NICE considers if QALYs gained under these circumstances ...
Belen Corbacho +2 more
core
Cell surface CD11c as a neutrophil aging marker molecule
FEBS Open Bio, EarlyView.Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
Evaluation of the experience led commissioning in end of life care project
, 2012 A pilot Experience Led Commissioning (ELC) for an end of life care project was evaluated independently by the University of Westminster. Overall, the evaluation uncovered favourable reports on the delivery of ELC.
Ridge, Damien T., Cheshire, A.
core
The Macmillan-Scottish ambulance partnership: driving change in end-of-life care. [PDF]
BMJ Support Palliat CareMcFerran E +5 more
europepmc +1 more source