Results 111 to 120 of about 611,597 (310)

Biomarkers Predicting Major Adverse Cardiovascular Events in End-Stage Kidney Disease: A Systematic Review

Kidney and Dialysis
Background: Cardiovascular disease is the leading cause of death in chronic kidney disease populations. The risk of major adverse cardiovascular events (MACE) is greater than that of progression to end-stage kidney disease.
Elin Mitford Davies, Morka Ezenwekere, Andrew J. Chetwynd, Louise Oni, Garry McDowell, Anirudh Rao   +5 more
doaj   +1 more source

End-Stage Kidney Disease Without Dialysis [PDF]

Health Affairs, 2015
Alvin H, Moss, Nancy, Armistead, Dale, Lupu   +2 more
openaire   +2 more sources

Global Challenge of Early Detection and Management of Chronic Kidney Disease [PDF]

, 2017
Chronic Kidney Disease (CKD) is a global health burden with a high economic cost to the health system and is an independent risk factor for cardiovascular disease (CVD), not only in the developed country but also in developing country like Indonesia.1,2
Fauziyati, A. (Ana)
core   +2 more sources

Computational Modeling Meets 3D Bioprinting: Emerging Synergies in Cardiovascular Disease Modeling

Advanced Healthcare Materials, EarlyView.
Emerging advances in three‐dimensional bioprinting and computational modeling are reshaping cardiovascular (CV) research by enabling more realistic, patient‐specific tissue platforms. This review surveys cutting‐edge approaches that merge biomimetic CV constructs with computational simulations to overcome the limitations of traditional models, improve ...
Tanmay Mukherjee, Mehdi Salar Amoli, Sarah Rezapourdamanab, Lama Rita El Shammas, Martin L. Tomov, Emilio A. Mendiola, Vahid Serpooshan, Reza Avazmohammadi   +7 more
wiley   +1 more source

Establishing a clinical phenotype for cachexia in end stage kidney disease - study protocol. [PDF]

, 2018
BACKGROUND: Surveys using traditional measures of nutritional status indicate that muscle wasting is common among persons with end-stage kidney disease (ESKD). Up to 75% of adults undergoing maintenance dialysis show some evidence of muscle wasting. ESKD
A Molfino, Adrian Slee, Alexander P. Maxwell, Andrew Davenport, C Drescher, C. McKeaveney, D Fouque, David S. Seres, Denis Fouque, Gary Adamson, Helen R. Noble, J Farkas, J Reid, J Reid, J Reid, J Reid, J Reid, JM Argiles, Joanne Reid, Joanne Shields, John Mallett, K Fearon, Kamyar Kalantar-Zadeh, Ken Farrington, L Barotfi, L Cuppari, L Radbruch, M Muscaritoli, Miles D. Witham, MK Barton, P Stenvinkel, RH Mak, S von Haehling, S von Haehling, S. Porter, WJ Evans, YP Jadeja   +36 more
core   +9 more sources

Biomimetic Copper‐Doped Nano‐Aluminum Adjuvant Potentiates Therapy in Chemoresistant Acute Myeloid Leukemia

Advanced Healthcare Materials, EarlyView.
We developed a novel copper‐doped aluminum nano‐adjuvant (CuNA) to overcome cytarabine resistance in acute myeloid leukemia (AML). CuNA effectively sensitizes drug‐resistant AML cells to cytarabine by inducing mitochondrial dysfunction and inhibiting HMGCR/GPX4 to amplify ferroptosis.
Chao He, Lingxiao Zhang, Yue Xiong, Yu Wang, Yuqing Zeng, Dandan Su, Ran Wang, Ying Li, Hongbo Chen, Fang Cheng, Zhi Ping Xu   +10 more
wiley   +1 more source

Effect of Blood Pressure Control on Long-Term Risk of End-Stage Renal Disease and Death Among Subgroups of Patients With Chronic Kidney Disease. [PDF]

, 2019
Background Our objective was to explore the effect of intensive blood pressure (BP) control on kidney and death outcomes among subgroups of patients with chronic kidney disease divided by baseline proteinuria, glomerular filtration rate, age, and body ...
Hsu, Chi-Yuan, Ku, Elaine, Lin, Feng, McCulloch, Charles E, Sarnak, Mark J, Smogorzewski, Miroslaw, Toto, Robert   +6 more
core  

Dual‐Peptide Nanoplatform: Mesoporous Silica Nanoparticles Functionalized With a Cell‐Penetrating Peptide and Loaded With Rationally Designed Antimicrobial Peptides for Tuberculosis Therapy

Advanced Healthcare Materials, EarlyView.
Machine learning–guided engineering of a plectasin‐derived peptide yields DC05, a potent antimycobacterial candidate. Encapsulation into tuftsin‐functionalized mesoporous silica nanoparticles enhances intracellular delivery, stability, and activity against Mycobacterium tuberculosis while maintaining low cytotoxicity and minimal hemolysis. The combined
Christian S. Carnero Canales, Cesar Augusto Roque‐Borda, Ana Carolina Cerqueira Negri, Oswaldo Ramirez Delgado, Letícia Oliveira Catarin Nunes, Flávia Aparecida Resende, Hernane Barud, Norival Alves Santos‐Filho, Saulo Santesso Garrido, Karen Cristina Oliveira, Alexandra Ivo de Medeiros, Rafael Miguel Sábio, Fernando Rogério Pavan   +12 more
wiley   +1 more source

Uraemic Atomatitis-A Rare Complication of End Stage Kidney Disease

Indian Journal of Kidney Diseases, 2022
Abid Ahmad Kuchay, M. P. Shamsudheen, Megha Saigal, Swarnalatha Guditi   +3 more
doaj   +1 more source

Small Extracellular Vesicles from Neural Cells: Physiological and Pathological Roles, and Potential in Neurodegenerative Therapy

Advanced Healthcare Materials, EarlyView.
Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim, Wei Zhang, Lyndsey Collins‐Praino, Yuling Wang, Andrew Care   +4 more
wiley   +1 more source