Results 101 to 110 of about 319,430 (262)

Gut Microbiota Regulates Systemic Inflammatory Response and Compensatory Anti‐Inflammatory Response Syndromes by Targeting PF4+ Macrophages in Acute Pancreatitis

Advanced Science, EarlyView.
ABSTRACT Acute pancreatitis (AP) begins with pancreatic local inflammation, leading to the onset of systemic inflammatory response syndrome (SIRS), followed by compensatory anti‐inflammatory response syndrome (CARS), which causes immune paralysis and higher mortality rate.
Liwei Liu, Guanqun Li, Dongxu Lu, Haoran Ding, Tianqi Lu, Yuhang Sui, Can Zhang, Yu Xie, Rui Kong, Hua Chen, Xuewei Bai, Hongtao Tan, Dongbo Xue, Xianzhi Meng, Le Li, Bei Sun   +15 more
wiley   +1 more source

Use of corticosteroids in Norwegian patients with immunoglobulin a nephropathy progressing to end-stage kidney disease: a retrospective cohort study

BMC Nephrology
Background Despite several clinical trials, the use of corticosteroid therapy for treating immunoglobulin A nephropathy (IgAN) remains controversial. We aimed to describe the use of corticosteroid therapy combined with supportive therapy in Norwegian ...
Mariell Rivedal, Yngvar Lunde Haaskjold, Øystein Eikrem, Rune Bjørneklett, Hans Peter Marti, Thomas Knoop   +5 more
doaj   +1 more source

Current Status of Kidney Replacement Therapy in Türkiye: A Summary of 2024 Turkish Society of Nephrology Registry Repor

Turkish Journal of Nephrology
Background: The Turkish Society of Nephrology registry annually collects nationwide data on hemodialysis, peritoneal dialysis (PD), and kidney transplantation.
Nurhan Seyahi, İsmail Koçyiğit, Mevlüt Tamer Dinçer, Necmi Eren, Halil Zeki Tonbul, Erhan Tatar, Zülfükar Yılmaz, Ebru Gök Oğuz, Ercan Türkmen, Kenan Ateş   +9 more
doaj   +1 more source

ERK‐Mediated Phosphorylation of YAP Defines a Noncanonical FGF Signaling Mechanism in Stem Cells

Advanced Science, EarlyView.
With a powerful combination of in vivo, ex vivo, and in vitro models, the authors highlight a novel FGF‐ERK signaling regulation of YAP at the S128 site in neural crest‐derived stem cells. This study opens exciting new directions in stem cell biology and craniofacial biology, paving the way for potential innovations in the treatment of craniofacial ...
Xiaolei Zhao, Shannon Erhardt, Li Tang, Xiaotong Chen, Stephen M Farmer, Zixiu Cheng, Wen Chen, Ella Ziyuan Lu, Kihan Sung, Chang‐Ru Tsai, Mingjie Zheng, Sheng Zhang, Yang Liu, Jianxin Wang, Min Li, James F Martin, Jun Wang   +16 more
wiley   +1 more source

End-Stage Kidney Disease Without Dialysis [PDF]

Health Affairs, 2015
Alvin H, Moss, Nancy, Armistead, Dale, Lupu   +2 more
openaire   +2 more sources

335 Fracture burden in paediatric end stage kidney disease

BMJ Paediatrics Open, 2021
Eugene Yu-hin Chan, Alison Lap-tak Ma, Samuel Chung-sum Ho, Ellen Yu, Matthew Hon-lam Lee, Yuet-ling Tung   +5 more
doaj   +1 more source

Marburg Virus Glycoprotein Is a Remarkable Virulent Factor Linked to Hemorrhagic Pathology: Evidence from Multimodal Experimental Systems

Advanced Science, EarlyView.
By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao, Hang Liu, Yanfeng Yao, Wei Deng, Jiawen Sun, Zhenyu Kang, Ashaq Ali, Chao Shan, Zhiming Yuan, Fei Deng, Hualin Wang, Yun‐Jia Ning   +11 more
wiley   +1 more source

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

Advanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang, Yi Sun, Yanxin Wang, Haijun Yan, Xiaoping Yue, Weidong Wu, Xueyu Chen, Jinfang Zhang, Yanbing Lin, Qiong Lei, Nan Ji, Shuaishuai Xing, Liqin Zeng, Qingzheng Kang, Depeng Zhao, Geng Guo, Huidong Zhang   +16 more
wiley   +1 more source

Prognostic Value of Hemoglobin Concentration on Renal Outcomes with Diabetic Kidney Disease: A Retrospective Cohort Study [Letter]

Diabetes, Metabolic Syndrome and Obesity
Chia-Ter Chao1–3 1Division of Nephrology, Department of Internal Medicine, Min-Sheng General Hospital, Taoyuan City, Taiwan; 2Division of Nephrology, Department of Internal Medicine, National Taiwan University Hospital and National Taiwan ...
Chao CT
doaj  

Chronic kidney disease onset, progression, and cardiovascular outcomes: proteomics informs biology and risk stratification

Cardiovascular Diabetology
Background Large-scale proteomics provides an opportunity to understand chronic kidney disease (CKD) and cardiovascular disease, yet research in this field is limited.
Jijuan Zhang, Hancheng Yu, Xingyue Song, Xianli Li, Jinchi Xie, Yuxiang Wang, Yue Li, Kun Xu, Gang Liu, Yunfei Liao, Xiong-Zhong Ruan, An Pan, Tingting Geng   +12 more
doaj   +1 more source