Results 41 to 50 of about 368,340 (301)

Dying from liver disease: the importance of end-of-life discussions [PDF]

, 2018
Over the past 50 years, deaths from liver disease have risen dramatically, whereas deaths from many other major diseases have fallen. Liver disease is now the third largest cause of premature death in the UK, with alcohol-related liver disease accounting
Watson, Sharan, Mortimore, Gerri
core   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

The Yin and the Yang of Hemostasis in End-Stage-Liver-Disease

Journal of Clinical Medicine, 2023
Patients with end stage liver disease (ESLD) undergoing liver transplantation are prone to thromboses both while on the waiting list or in the perioperative period. This hypercoagulability is associated with significant endothelial dysfunction (ED) due to nitric oxide dysregulation.
Fuat H. Saner, Ecaterina Scarlatescu, Dieter Clemens Broering, Dmitri Bezinover   +3 more
openaire   +2 more sources

Alcohol-Related End-Stage Liver Disease and Transplantation: The Debate Continues

, 1994
Liver transplantation has been an acceptable treatment for end-stage liver disease for many years. The greatest number of patients needing transplantation for survival are those suffering from alcohol-related end-stage liver disease. Throughout the years,
Kelso, Lynn A.
core   +1 more source

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho, Karim M. Soliman, Wisit Cheungpasitporn, Wannasit Wathanavasin, Ahmed Daoud, Ahmed I. Kamal, Balázs Szamosfalvi, Tibor Fülöp   +7 more
wiley   +1 more source

Low sphingosine-1-phosphate plasma levels are predictive for increased mortality in patients with liver cirrhosis. [PDF]

PLoS ONE, 2017
BACKGROUND & AIM:The association of circulating sphingosine-1-phosphate (S1P), a bioactive lipid involved in various cellular processes, and related metabolites such as sphinganine-1-phosphate (SA1P) and sphingosine (SPH) with mortality in patients with ...
Susen Becker, Benedict Kinny-Köster, Michael Bartels, Markus Scholz, Daniel Seehofer, Thomas Berg, Cornelius Engelmann, Joachim Thiery, Uta Ceglarek, Thorsten Kaiser   +9 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Cognitive impairment in patients awaiting kidney and liver transplantation—A clinically relevant problem?

Brain and Behavior
Introduction Cognitive impairment (CI) is common in both end‐stage kidney disease (ESKD) and alcohol‐related liver cirrhosis. The aim of this study was to assess the prevalence and patterns of CI in patients awaiting kidney and liver transplantation, and
Aleksandra Golenia, Piotr Olejnik, Magdalena Grusiecka‐Stańczyk, Norbert Żołek, Ewa Wojtaszek, Paweł Żebrowski, Joanna Raszeja‐Wyszomirska, Jolanta Małyszko   +7 more
doaj   +1 more source

Serial assessment of hepatic encephalopathy in patients hospitalised for acute decompensation of cirrhosis

Annals of Hepatology, 2019
Introduction and aim: Hepatic encephalopathy (HE) is a frequent complication of cirrhosis, but the clinical and prognostic significance of the progression of mental status in hospitalised cirrhotics is unknown.
Dariana C. Maggi, Ariane Borgonovo, Emília T. Bansho, Pedro E. Soares-Silva, Telma E. Silva, Bruno S. Colombo, Letícia M. Wildner, Maria L. Bazzo, Esther B. Dantas-Correa, Janaína L. Narciso-Schiavon, Leonardo L. Schiavon   +10 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source