Results 51 to 60 of about 368,340 (301)
Liver transplantation for primary biliary cholangitis (review)
Вестник трансплантологии и искусственных органов, 2022 Primary biliary cholangitis (PBC) is an autoimmune liver disease resulting from the destruction and inflammation of intrahepatic bile ducts. This end-stage disease was once the most common cause of liver transplantation.
I. M. Iljinsky, O. M. Tsirulnikova
doaj +1 more source
, 1998 Background: The success of orthotopic liver transplantation as treatment for end-stage liver disease has prompted investigation of strategies to maintain or improve nutrition and growth in children awaiting transplantation, because malnutrition is an ...
Cleghorn, GJ +7 more
core +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Effect of end-stage liver disease on left atrial function
Al-Azhar Assiut Medical Journal, 2020 Background Hepatic cirrhosis causes structural and functional myocardial changes. Parameters of left atrial (LA) function provided novel insights and have prognostic significance in many cardiac patients.
Eman R Zaki +3 more
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Successful Liver Transplantation in Two Polish Brothers with Transaldolase Deficiency
Children, 2021 Transaldolase deficiency (TALDO; OMIM 606003) is a rare inborn autosomal-recessive error of the pentose phosphate pathway. It is an early-onset multisystem disease with dysmorphic features, anaemia, coagulopathy, thrombocytopenia, tubulopathy ...
Marek Stefanowicz +7 more
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Utility of Serum YKL-40 as a Tumor-Specific Marker of Hepatobiliary Malignancies
Gut and Liver, 2010 Background/Aims: Serum YKL-40 has been linked to several human cancers. We investigated the potential role of serum YKL-40 as a marker of hepatobiliary malignancies.
doaj +1 more source
, 2015 BACKGROUND Endothelial glycocalyx participates in the maintenance of vascular integrity, and its perturbations cause capillary leakage, loss of vascular responsiveness, and enhanced adhesion of leukocytes and platelets.
Berlakovich, Gabriela +6 more
core +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Invasive fungal disease in patients with end-stage liver disease
Infectious Diseases & Immunity. Invasive fungal disease (IFD) has become a critical complication in patients with end-stage liver disease (ESLD), marked by a rising prevalence and the emergence of drug-resistant strains in recent decades.
Yi-Ran Shou, Zheng-Yin Liu, Haijuan Wang
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