Results 61 to 70 of about 768,450 (337)

A five-year longitudinal study of the relation between end-stage kidney disease as the outcomes

BMC Nephrology, 2020
Background Patients with end-stage kidney disease (ESKD) are required to undergo consecutive time-based blood and biochemical tests to determine the progression of the disease according to changes in their blood and biochemical data.
Hsiu-Lan Li, Pei-Hui Tai, Yi-Ting Hwang, Shih-Wei Lin   +3 more
doaj   +1 more source

A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer

Molecular Oncology, EarlyView.
Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla, Jana R. Crespo, Saioa Garcia‐Longarte, Marta Fidalgo, Sara del Palacio, Natalia Martin‐Martin, Onintza Carlevaris, Ianire Astobiza, Sonia Fernández‐Ruiz, Marc Guiu, Laura Bárcena, Isabel Mendizabal, Ana M. Aransay, Mariona Graupera, Roger R. Gomis, Arkaitz Carracedo   +15 more
wiley   +1 more source

Pulmonary embolism in chronic kidney disease and end-stage renal disease hospitalizations: Trends, outcomes, and predictors of mortality in the United States

SAGE Open Medicine, 2021
Background: It is well-known that patients with chronic kidney disease and end-stage renal disease are at increased risk of pulmonary embolism than patients with normal kidney function.
Jagmeet Singh, Sushmita Khadka, Dhanshree Solanki, Asim Kichloo, Harshil Shah, Manasee J Vyas, Savneek Chugh, Neil Patel, Shantanu Solanki   +8 more
doaj   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Chronic inflammation in end-stage renal disease and dialysis

Nephrology, Dialysis and Transplantation, 2018
Under normal conditions, inflammation is a protective and physiological response to various harmful stimuli. However, in several chronic debilitating disorders, such as chronic kidney disease, inflammation becomes maladaptive, uncontrolled and persistent.
G. Cobo, B. Lindholm, P. Stenvinkel
semanticscholar   +1 more source

Renal replacement modality and stroke risk in end-stage renal disease—a national registry study [PDF]

, 2017
Background: The risk of stroke in end-stage renal disease (ESRD) on renal replacement therapy (RRT) is up to 10-fold greater than the general population. However, whether this increased risk differs by RRT modality is unclear.
Dawson, Jesse, Findlay, Mark, MacIsaac, Rachael, MacLeod, Mary Joan, Mark, Patrick B., Metcalfe, Wendy, Traynor, Jamie P.   +6 more
core   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

United States Renal Data System public health surveillance of chronic kidney disease and end-stage renal disease

Kidney international. Supplement, 2015
The United States Renal Data System (USRDS) began in 1989 through US Congressional authorization under National Institutes of Health competitive contracting.
A. Collins, R. Foley, D. Gilbertson, Shu‐Cheng Chen   +3 more
semanticscholar   +1 more source

Magnitude of the Difference Between Clinic and Ambulatory Blood Pressures and Risk of Adverse Outcomes in Patients With Chronic Kidney Disease. [PDF]

, 2019
Background Obtaining 24-hour ambulatory blood pressure ( BP ) is recommended for the detection of masked or white-coat hypertension. Our objective was to determine whether the magnitude of the difference between ambulatory and clinic BP s has prognostic ...
Bae, Se Ri, Grimes, Barbara A, Hsu, Raymond K, Ku, Elaine, Lipkowitz, Michael S, Smogorzewski, Miroslaw J, Tuot, Delphine S, Weir, Matthew R   +7 more
core   +1 more source

The prognostic importance of chronic end-stage diseases in geriatric patients admitted to 163 Italian ICUs [PDF]

, 2017
BACKGROUND: The number of elderly patients undergoing major surgical interventions and then needing admission to intensive care unit (ICU) grows steadily.
Alampi, Daniela, Bertolini, G., DE BLASI, Roberto Alberto, Finazzi, S., Giviti,, Gristina, G., Livigni, S., Malacarne, P., Mannoni, R., Nattino, G., Poole, D., Radrizzani, D., Sorgato, C   +12 more
core   +1 more source