Results 151 to 160 of about 4,687,816 (246)

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

ViViMZheimer a slice based end to end model for Alzheimer's disease diagnosis from 3D MRI. [PDF]

Sci Rep
Zhou J, Wan J, Chen X, Li X, Wu Z, Zhang Z, Zhang C.   +6 more
europepmc   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Iliac end-to-end structural autograft for complex failure after occipital cervical fusion: illustrative case. [PDF]

J Neurosurg Case Lessons
Patel P, Tjauw M, Burke JF.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

A dynamic anthropomorphic phantom for end-to-end testing in image- and surface-guided adaptive radiotherapy. [PDF]

Med Phys
Bakhtiari Moghaddam A, Runz A, Augusto RF, Echner G, Johnen W, Gabriel R, Haering P, Lang C, Seeber S, Murillo C, Ackermann B, Pestana R, Beyer C, Weykamp F, Jochim M, Qubala A, Batista V, Jäkel O, Karger CP.   +18 more
europepmc   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Erratum: End-to-end characterization of AAV manufacturing process using charge detection mass spectrometry. [PDF]

Mol Ther Methods Clin Dev
Young LM, Draper BE, Jarrold MF, Froelich CA, Motevalian SP.   +4 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

StarWhisper Telescope: an AI framework for automating end-to-end astronomical observations. [PDF]

Commun Eng
Wang C, Zhang Y, Li Y, Hu X, Mao Y, Chen X, Du P, Wang R, Wu Y, Yang H, Li Y, Wang B, Mu H, Chen X, He S, Mo H, Zhang L, Du L, Zhao Y, Tian J, Ge L, Mao Y, Li S, Wang Z, Lu X, Zou J, Huang Y, Sun N, Zheng J, He M, Bai Y, Jin J, Wu H, Liu J.   +33 more
europepmc   +1 more source