Results 81 to 90 of about 3,009,219 (314)

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

A deployable LoRa-based end-to-end monitoring architecture for commercial beef cattle barns under limited-connectivity conditions

Journal of Agriculture and Food Research
Reliable barn environmental monitoring is essential for animal welfare, heat-load assessment, ventilation management, and data-driven decision-making in commercial beef cattle production.
Guang Yi, Xilin Wang, Songyu Jiang, Tengfei He, Zhaohui Chen   +4 more
doaj   +1 more source

Compensation of a ball end tool trajectory in complex surface milling [PDF]

, 2012
This work is consecrated to the minimising of machining errors based on a method for the compensation of the trajectory to be machined in hemispherical milling.
Baili, Maher, Smaoui, Moez, Zghal, Ali, Dessein, Gilles, Bouaziz, Zoubeir   +4 more
core  

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Minimal regularity conditions for the end-point estimate of bilinear Calderón-Zygmund operators

Proceedings of the American Mathematical Society, Series B, 2014
Minimal regularity conditions on the kernels of bilinear operators are identified and shown to be sufficient for the existence of end-point estimates within the context of the bilinear Calderón-Zygmund theory.
Carlos Pérez, Rodolfo H. Torres
doaj   +1 more source

A practical proposal to obtain solutions of certain variational problems avoiding Euler formalism

Heliyon, 2020
The aim of this article is to show the way to get both, exact and analytical approximate solutions for certain variational problems with moving boundaries but without resorting to Euler formalism at all, for which we propose two methods: the Moving ...
U. Filobello-Nino, H. Vazquez-Leal, J. Huerta-Chua, R.A. Callejas-Molina, M.A. Sandoval-Hernandez   +4 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Heat endurance and impact resistance: Investigating fibrous engineered cementitious composites under impact loads at elevated temperatures

Case Studies in Construction Materials
This study presents experimental findings that assess the influence of boundary end conditions on the response of engineered cementitious composites (ECC) reinforced plates under impact loading, both before and after exposure to elevated temperatures ...
Sallal R. Abid, Raad A. Al-Ameri, G. Murali, Sajjad H. Ali, Mustafa Özakça   +4 more
doaj   +1 more source

End-to-end learning of adaptive coded modulation schemes for resilient wireless communications [PDF]

Adaptive modulation and coding schemes play a crucial role in ensuring robust data transfer in wireless communications, especially when faced with changes or interference in the transmission channel. These schemes involve the use of variable coding rates,
Deo, Ravinesh C., Soar, Jeffrey, Davey, Christopher P., Sharma, Ekta, Shakeel, Ismail, Salcedo-sanz, Sancho   +5 more
core   +1 more source