Results 111 to 120 of about 427,262 (303)
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Learning-based position control of a closed-kinematic chain robot end-effector [PDF]
A trajectory control scheme whose design is based on learning theory, for a six-degree-of-freedom (DOF) robot end-effector built to study robotic assembly of NASA hardwares in space is presented.
Nguyen, Charles C., Zhou, Zhen-Lei
core +1 more source
A Self-Organizing Neural Model of Motor Equivalent Reaching and Tool Use by a Multijoint Arm [PDF]
, 1992 This paper describes a self-organizing neural model for eye-hand coordination. Called the DIRECT model, it embodies a solution of the classical motor equivalence problem. Motor equivalence computations allow humans and other animals to flexibly employ an
Bullock, Daniel +2 more
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Proposal end effector for industrial robot [PDF]
, 2016 Tato bakalářská práce se zabývá rozdělením koncových efektorů používaných v průmyslové robotice. V úvodní části práce jsou popsány základní druhy průmyslových robotů.
Dvorník, Jan
core
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Optimal workplacement for robotic friction stir welding task [PDF]
, 2013 Robotic manipulators are widely used in industry for welding processes. Inadequate joint stiffness in the manipulators often limits their use for high quality welding operations because of the deformation errors produced during the process.
ABBA, Gabriel, JAIN, Achin, QIN, Jinna
core +4 more sources
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Design for a Three-Fingered Hand [PDF]
A general purpose end-effector for use on the space manipulator proposed for the shuttle program was developed. The end-effector has the capabilities of a human hand and peel-off value as a human prosthetic device.
Crossley, F. R. E., Umholtz, F. G.
core +1 more source