Results 161 to 170 of about 280,629 (216)
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2008 openaire +2 more sources
Some of the next articles are maybe not open access.
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Narrative Inquiry in Bioethics, 2013
This narrative symposium examines the relationship of bioethics practice to personal experiences of illness. A call for stories was developed by Tod Chambers, the symposium editor, and editorial staff and was sent to several commonly used bioethics listservs and posted on the Narrative Inquiry in Bioethics website.
openaire +2 more sources
This narrative symposium examines the relationship of bioethics practice to personal experiences of illness. A call for stories was developed by Tod Chambers, the symposium editor, and editorial staff and was sent to several commonly used bioethics listservs and posted on the Narrative Inquiry in Bioethics website.
openaire +2 more sources
2005
Under the new European WEEE directive there will be strict limits for disposal of electrical goods to landfill. The area of analysis which takes into account the full life cycle of products and components is called "end of life" analysis. The idea is that the economic life of components is longer than the life of the initial use.
Wynn, H. +4 more
openaire +3 more sources
Under the new European WEEE directive there will be strict limits for disposal of electrical goods to landfill. The area of analysis which takes into account the full life cycle of products and components is called "end of life" analysis. The idea is that the economic life of components is longer than the life of the initial use.
Wynn, H. +4 more
openaire +3 more sources
BMJ, 2014
US physicians are more pressed than ever to deal with end of life care.
openaire +2 more sources
US physicians are more pressed than ever to deal with end of life care.
openaire +2 more sources
American Journal of Hospice and Palliative Medicine®, 2021
Background: Oncology provider discussions of treatment options, outcomes of treatment, and end of life planning are essential to care for patients with advanced malignancies. Studies have shown that despite this, many patients do not have adequate care planning, including end of life planning. It is thought that
Natasha Ansari +3 more
openaire +2 more sources
Background: Oncology provider discussions of treatment options, outcomes of treatment, and end of life planning are essential to care for patients with advanced malignancies. Studies have shown that despite this, many patients do not have adequate care planning, including end of life planning. It is thought that
Natasha Ansari +3 more
openaire +2 more sources
End-of-life dialogue, end-of-life education
BMJ Supportive & Palliative Care, 2014I read with particular interest the recent letter from Dr Fenning1 about the importance of identifying the ‘end-of-life’ (EOL) period in everyday medical practice. Working with geriatric patients in an acute geriatric clinic on the Italian territory, I directly experience the unpredictable impact of multimorbidity and chronic progressive conditions on ...
openaire +3 more sources
Nursing Management, 2005
Those with a role in end of life care management might find the resources part of the NHS End of Life Care Programme website useful.
Janet, Craig, Walter J, Jones
openaire +4 more sources
Those with a role in end of life care management might find the resources part of the NHS End of Life Care Programme website useful.
Janet, Craig, Walter J, Jones
openaire +4 more sources