Results 201 to 210 of about 2,253,032 (266)

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Comments on: 'End-of-Life Care Preferences of Terminally Ill Patients: A Cross-sectional Study'. [PDF]

Indian J Palliat Care
Saudella ET.
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Potentially burdensome end-of-life care for colorectal cancer decedents: A retrospective cohort study. [PDF]

Palliat Support Care
Varghese G, Okuba T, Delaney G, Arnolda G, Liauw W, Lystad R, Harrison R, Braithwaite J, Mitchell R.   +8 more
europepmc   +1 more source

Supporting homecare workers to provide palliative and end-of-life care: A scoping review of interventions and their implementation. [PDF]

Palliat Care Soc Pract
Williamson LE, Dhawan A, Mujtabah F, Yeung AQK, Leverton M, Sleeman KE, Burgess A, Ellis-Smith C, Evans CJ.   +8 more
europepmc   +1 more source

Between culture and care: nurses' experiences of end-of-life communication in Ghana. [PDF]

BMC Med Ethics
Aidoo P, Attafuah PYA, Kpolar WO, Ohene LA.   +3 more
europepmc   +1 more source

Access to organ donation in paediatric intensive care is shaped by end-of-life trajectories. [PDF]

BMJ Paediatr Open
Perenyi C, Baleine JF, Cambonie G, Gaudaire A, Milési C, Mounier S, Quintane M, Vachiery Lahaye F, Gavotto A.   +8 more
europepmc   +1 more source

Beyond emotional regulation: Expanding the existential dimensions of emotional labor in end-of-life care. [PDF]

Palliat Support Care
Muqoddam F, Bawono Y, Johansyah OI.
europepmc   +1 more source