Results 61 to 70 of about 3,892,230 (280)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
End-of-life care in the United States: policy issues and model programs of integrated care
Background: End-of-life care financing and delivery in the United States is fragmented and uncoordinated, with little integration of acute and long-term care services.
Joshua M. Wiener, Jane Tilly
doaj +3 more sources
Terminally ill patients experience conditions of life that can become unbearable resulting in the wish to end their life prematurely. One way to end one’s life prematurely is by voluntary stopping of eating and drinking, however this can also be ...
Cíntia Pinho-Reis, Manuel Luís Capelas
doaj +1 more source
A Same-Sex Couple Copes With End-of-Life Issues: A Case Materials Guide
Medical students in the United States receive a median of only 5 hours of instruction on lesbian, gay, bisexual, and transgender–related health topics during medical school.
Colby Croft +5 more
doaj +1 more source
Family members’ perceptions of end-of-life care across diverse locations of care [PDF]
Background: The goal of the study was to assess perceived level of satisfaction with end-of-life care, focusing on the last 48 hours of life. Methods: A previously validated instrument was used in a telephone survey with bereaved family members (n=
Gallagher, Romayne, Krawczyk, Marian
core +2 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Knowledge About and Attitudes towards End of Life Care for Gay, Lesbian, Bisexual & Transgender People (Phase 2) [PDF]
Increasing evidence suggests that many gay, lesbian, bisexual and transgender (GLBT) people are being denied their legal rights in their own end-of-life care and the end-of-life care of their partners and other important people in their lives. A study in
Colleen Cartwright +2 more
core
On Pediatric Vaccines and Catholic Social Teaching [PDF]
Determining whether, and when, to get one\u27s children vaccinated has become an increasingly controversial decision, often leaving parents fearful of making the “wrong” choice.
Bilgrien +20 more
core +2 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source

