Results 51 to 60 of about 9,261,553 (282)
An Interactive Fuzzy Satisficing Method for Fuzzy Random Multiobjective 0-1 Programming Problems through Probability Maximization Using Possibility [PDF]
, 2009 In this paper, we focus on multiobjective 0-1 programming problems under the situation where stochastic uncertainty and vagueness exist at the same time.
Matsui, Takeshi +3 more
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
MathematicsThis study tests whether the random-parameter structure of a Multinomial Logit crash-type model is itself spatially stable, using individual-level likelihood-ratio tests estimated separately for Ankara (28,825 crashes) and İzmir (24,280 crashes) between ...
Tamkin Karimi, Mahmut Esad Ergin
doaj +1 more source
Shock and Vibration, 2018 Nondeterministic parameters of certain distribution are employed to model structural uncertainties, which are usually assumed as stochastic factors. However, model parameters may not be precisely represented due to some factors in engineering practices ...
Xingfa Yang +4 more
doaj +1 more source
On the strong convergence for weighted sums of asymptotically almost negatively associated random variables [PDF]
, 2014 summary:Applying the moment inequality of asymptotically almost negatively associated (AANA, in short) random variables which was obtained by Yuan and An (2009), some strong convergence results for weighted sums of AANA random variables are obtained ...
Deng, Guangming +3 more
core +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Estimating ordered categorical variables using panel data: a generalized ordered probit model with an autofit procedure [PDF]
Estimation procedures for ordered categories usually assume that the estimated coefficients of independent variables do not vary between the categories (parallel-lines assumption).
Andreas Schmid +2 more
core +4 more sources
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
What Is the Spectral Theory of Random Fields?
Austrian Journal of StatisticsWe review the current state of the spectral theory of random functions of several variables created by Professor M. I. Yadrenko at the end of 1950s. It turns out that the spectral expansions of multi-dimensional homogeneous and isotropic random fields ...
Anatoliy Malyarenko
doaj +1 more source