Results 61 to 70 of about 9,261,553 (282)
Baseline and Dynamic Risk Predictors of Appropriate Implantable Cardioverter Defibrillator Therapy
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020 Background Current approaches fail to separate patients at high versus low risk for ventricular arrhythmias owing to overreliance on a snapshot left ventricular ejection fraction measure. We used statistical machine learning to identify important cardiac
Katherine C. Wu +9 more
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Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Extremes of Product of Gaussian Random Variables
AxiomsWe investigate the asymptotic behavior of the product of Gaussian random variables, with a focus on tail probabilities. Although sums of normal variables are well understood through classical limit theorems, their products exhibit significantly more ...
Džiugas Chvoinikov +2 more
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Advances in Mechanical Engineering, 2019 The robust design optimization of an airfoil needs to continuously realize the probability-based aerodynamic simulation for various combinations of geometry and wind climate parameters.
Xufang Zhang, Zhenguang Wu, Wei He
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Understanding Interdependency Through Complex Information Sharing
Entropy, 2016 The interactions between three or more random variables are often nontrivial, poorly understood and, yet, are paramount for future advances in fields such as network information theory, neuroscience and genetics.
Fernando Rosas +4 more
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A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Известия высших учебных заведений. Поволжский регион:Технические наукиBackground. The object of this study is mathematical models used to calculate the temporal characteristics of the start and end of actions in an information and telecommunications system under the influence of random factors.
M.M. Butaev
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Fast Generation of Discrete Random Variables [PDF]
We describe two methods and provide C programs for generating discrete random variables with functions that are simple and fast, averaging ten times as fast as published methods and more than five times as fast as the fastest of those. We provide general
George Marsaglia +2 more
core
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source